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Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain.

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Paul Raj R, Behari J, Rao AR · 1999

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Young rats showed brain chemistry changes after 35 days of RF exposure at levels similar to cell phone use.

Plain English Summary

Summary written for general audiences

Researchers exposed young rats to radiofrequency radiation at cell phone-like levels for 35 days and found significant changes in brain chemistry, including increased calcium movement and enzyme activity. These cellular changes in developing brains suggest RF exposure during growth may disrupt normal brain function.

Why This Matters

This study adds important evidence to our understanding of how RF radiation affects the developing brain. The researchers found measurable biochemical changes at a specific absorption rate of 0.75 W/kg, which falls within the range of typical cell phone exposures (SAR limits are 1.6 W/kg in the US). What makes this research particularly significant is the focus on young, developing animals and the 35-day exposure period, which better reflects real-world chronic exposure patterns than acute studies. The changes in calcium ion efflux and ornithine decarboxylase activity are concerning because both play crucial roles in brain development and cellular communication. While this is animal research and we must be cautious about direct extrapolation to humans, the findings align with a growing body of evidence suggesting that developing brains may be more vulnerable to RF effects than previously assumed.

Exposure Details

SAR
0.75 W/kg
Power Density
1 µW/m²
Source/Device
112 MHz
Exposure Duration
35 days

Exposure Context

This study used 1 µW/m² for radio frequency:

This study used 0.75 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 1 µW/m²Extreme Concern1,000 uW/m2FCC Limit10M uW/m2Effects observed in the Slight Concern range (Building Biology)FCC limit is 10,000,000x higher than this exposure level

Study Details

The effect of exposing rats to amplitude modulated radiofrequency radiation (112 MHz modulated to 16 Hz) during development and growth has been examined.

Wistar rats (35 days old) when exposed at above frequency at the power level 1.0 mW/cm2 (SAR, 0.75 W...

Cite This Study
Paul Raj R, Behari J, Rao AR (1999). Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain. Indian J Biochem Biophys 36(5):337-340, 1999.
Show BibTeX
@article{r_1999_effect_of_amplitude_modulated_1256,
  author = {Paul Raj R and Behari J and Rao AR},
  title = {Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain.},
  year = {1999},
  
  url = {http://nopr.niscair.res.in/handle/123456789/15468},
}

Quick Questions About This Study

Researchers exposed young rats to radiofrequency radiation at cell phone-like levels for 35 days and found significant changes in brain chemistry, including increased calcium movement and enzyme activity. These cellular changes in developing brains suggest RF exposure during growth may disrupt normal brain function.