Nonthermal GSM microwaves affect chromatin conformation in human lymphocytes similar to heat shock.
Sarimov R, Malmgren L.O.G., Markova, E., Persson, B.R.R.. Belyaev, I.Y. · 2004
View Original AbstractGSM microwaves changed chromatin conformation in human lymphocytes in a pattern similar to heat shock, with effects varying by frequency and donor.
Plain English Summary
Researchers exposed lymphocytes from seven healthy persons to GSM microwaves at different frequencies in the range of 895-915 MHz and measured changes in chromatin conformation. A 30-min exposure at 900 and 905 MHz produced statistically significant condensation of chromatin in lymphocytes from 1 of 3 tested donors. Stronger effects were found following 1-h exposure, with chromatin condensation in 3 donors and decondensation in 1 donor. The observed chromatin changes were similar to effects of heat shock within the temperature window of 40/spl deg/C-44/spl deg/C.
Why This Matters
Exposure was performed in a transverse electromagnetic transmission line cell (TEM-cell) using a GSM test-mobile phone, with all standard modulations including 2 W output power in the pulses and a specific absorbed rate (SAR) of 5.4 mW/kg. Changes in chromatin conformation were measured by the method of anomalous viscosity time dependencies (AVTD), which the researchers describe as indicative of stress response and genotoxic effects. Heat shock and the genotoxic agent camptothecin were used as positive controls. In replicated experiments, cells from four out of five donors responded to 905 MHz, while responses to 915 MHz were observed in cells from 1 out of 5 donors, p<0.002. The effects of microwaves correlated statistically significantly with effects of heat shock and the initial state of chromatin before exposure.
Exposure Details
- SAR
- 0.0054 W/kg
- Source/Device
- 895–915 MHz GSM test-mobile phone
- Exposure Duration
- 30 min or 1 h
Where This Falls on the Concern Scale
Study Details
To investigate whether microwaves (MWs) of Global System for Mobile Communication (GSM) induce changes in chromatin conformation in human lymphocytes.
Effects of MWs were studied at different frequencies in the range of 895-915 MHz in experiments with...
30-min exposure to MWs at 900 and 905 MHz resulted in statistically significant condensation of chro...
The conclusion-GSM microwaves under specific conditions of exposure affected human lymphocytes similar to stress response. The data suggested that the MW effects differ at various GSM frequencies and vary between donors.
Show BibTeX
@article{r_2004_nonthermal_gsm_microwaves_affect_43,
author = {Sarimov R and Malmgren L.O.G. and Markova and E. and Persson and B.R.R.. Belyaev and I.Y.},
title = {Nonthermal GSM microwaves affect chromatin conformation in human lymphocytes similar to heat shock.},
year = {2004},
url = {https://ieeexplore.ieee.org/abstract/document/1341526},
}