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Response, thermal regulatory threshold and thermal breakdown threshold of restrained RF-exposed mice at 905 MHz.

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Ebert S, Eom SJ, Schuderer J, Apostel U, Tillmann T, Dasenbrock C, Kuster N. · 2005

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In restrained mice exposed to 905 MHz radiofrequency fields, thermal regulatory breakdown may occur at SAR levels of 6 W kg(-1) under laboratory conditions.

Plain English Summary

Summary written for general audiences

This study determined the thermal regulatory and thermal breakdown thresholds for in-tube restrained B6C3F1 and NMRI mice exposed to radiofrequency electromagnetic fields at 905 MHz. The thermal regulatory threshold of the restrained mice was found at SAR levels between 2 W kg(-1) and 5 W kg(-1). The breakdown of regulation was determined at 10.1 +/- 4.0 W kg(-1) for B6C3F1 mice and 7.7 +/- 1.6 W kg(-1) for NMRI mice. NMRI mice were more sensitive to thermal stress and responded at lower SAR values with regulation and breakdown.

Why This Matters

Mice were placed inside a 'Ferris Wheel' exposure setup at 22 +/- 2 degrees C and 30-70% humidity, and rectal temperature was measured prior, during and after the 2 h exposure session. The whole-body averaged specific absorption rate levels applied were SAR = 0, 2, 5, 7.2, 10, 12.6 and 20 W kg(-1). For B6C3F1 mice, the thermal response was examined for three different weight groups (20 g, 24 g, 29 g), both genders and for pregnant mice. Based on a simplified power balance equation, the thresholds show a clear dependence upon the metabolic rate and weight.

Exposure Details

SAR
0, 2, 5, 7.2, 10, 12.6 and 20 W/kg
Source/Device
905 MHz
Exposure Duration
2 Hours

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kg
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 905 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 905 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The objective of this study was the determination of the thermal regulatory and the thermal breakdown thresholds for in-tube restrained B6C3F1 and NMRI mice exposed to radiofrequency electromagnetic fields at 905 MHz.

Different levels of the whole-body averaged specific absorption rate (SAR = 0, 2, 5, 7.2, 10, 12.6 a...

The thermal regulatory threshold of in-tube restrained mice was found at SAR levels between 2 W kg(-...

The presented data suggest that the thermal breakdown for in-tube restrained mice, whole-body exposed to radiofrequency fields, may occur at SAR levels of 6 W kg(-1)(K = 2) at laboratory conditions.

Cite This Study
Ebert S, Eom SJ, Schuderer J, Apostel U, Tillmann T, Dasenbrock C, Kuster N. (2005). Response, thermal regulatory threshold and thermal breakdown threshold of restrained RF-exposed mice at 905 MHz. Phys Med Biol. 50(21):5203-5215, 2005.
Show BibTeX
@article{s_2005_response_thermal_regulatory_threshold_959,
  author = {Ebert S and Eom SJ and Schuderer J and Apostel U and Tillmann T and Dasenbrock C and Kuster N.},
  title = {Response, thermal regulatory threshold and thermal breakdown threshold of restrained RF-exposed mice at 905 MHz.},
  year = {2005},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/16237250/},
}
PubMed: 16237250

Cited By (39 papers)

Quick Questions About This Study

The study used B6C3F1 and NMRI mice, held in restraint tubes during radiofrequency exposure at 905 MHz.
The breakdown of regulation was determined at 10.1 +/- 4.0 W kg(-1) for B6C3F1 mice and 7.7 +/- 1.6 W kg(-1) for NMRI mice.
NMRI mice were more sensitive to thermal stress and responded at lower SAR values with regulation and breakdown.
Thermal responses were assessed by measurement of the rectal temperature prior, during and after the 2 h exposure session.
The thresholds show a clear dependence upon the metabolic rate and weight.