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Effect of exposure to 50 Hz magnetic field with or without insulin on blood-brain barrier permeability in streptozotocin-induced diabetic rats.

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Gulturk S, Demirkazik A, Kosar I, Cetin A, Dökmetas HS, Demir T · 2010

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Power frequency magnetic fields can weaken the brain's protective barrier, with diabetics showing the most severe effects.

Plain English Summary

Summary written for general audiences

Researchers exposed diabetic rats to power line frequency magnetic fields for 30 days. The magnetic fields weakened the blood-brain barrier, which normally protects the brain from harmful substances. Diabetic animals with magnetic field exposure showed the worst barrier damage, potentially allowing toxins easier brain access.

Why This Matters

This study reveals a concerning interaction between power frequency magnetic fields and metabolic health that deserves attention. The 5 milliTesla exposure level used here is significantly higher than typical household exposures (usually 0.1-1 mT near appliances), but it's within ranges found near power lines or electrical equipment. What makes this research particularly relevant is how it demonstrates that EMF effects may be amplified in people with existing health conditions like diabetes. The blood-brain barrier serves as your brain's security system, and when it becomes more permeable, toxins and other harmful substances can more easily reach brain tissue. The fact that insulin treatment partially protected against this EMF-induced barrier breakdown suggests the mechanism involves metabolic pathways, adding another layer to our understanding of how electromagnetic fields affect biological systems.

Exposure Details

Magnetic Field
5 mG
Source/Device
50 Hz
Exposure Duration
65 min every day for 30 days

Exposure Context

This study used 5 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 5 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 400x higher than this exposure level

Study Details

We investigated the effect of long‐term exposure to modulation magnetic field (MF), insulin, and their combination on blood–brain barrier (BBB) permeability in a diabetic rat model.

Fifty‐three rats were randomly assigned to one of six groups: sham, exposed to no MF; MF, exposed to...

The extravasation of brain EB of the MF, DM, DMMF, DMI, and DMIMF groups was higher than that of the...

Cite This Study
Gulturk S, Demirkazik A, Kosar I, Cetin A, Dökmetas HS, Demir T (2010). Effect of exposure to 50 Hz magnetic field with or without insulin on blood-brain barrier permeability in streptozotocin-induced diabetic rats. Bioelectromagnetics. 31(4):262-269, 2010.
Show BibTeX
@article{s_2010_effect_of_exposure_to_254,
  author = {Gulturk S and Demirkazik A and Kosar I and Cetin A and Dökmetas HS and Demir T},
  title = {Effect of exposure to 50 Hz magnetic field with or without insulin on blood-brain barrier permeability in streptozotocin-induced diabetic rats.},
  year = {2010},
  doi = {10.1002/bem.20557},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.20557},
}

Quick Questions About This Study

Researchers exposed diabetic rats to power line frequency magnetic fields for 30 days. The magnetic fields weakened the blood-brain barrier, which normally protects the brain from harmful substances. Diabetic animals with magnetic field exposure showed the worst barrier damage, potentially allowing toxins easier brain access.