Evaluation of genotoxic effects in male Wistar rats following microwave exposure.
Kumar S, Kesari KK, Behari J. · 2010
View Original AbstractWistar rats exposed to microwaves at 10 GHz or 50 GHz for 45 days showed micronuclei formation, increased ROS production, and changes in antioxidant enzyme levels.
Plain English Summary
Wistar rats were exposed to microwaves for 2 hours a day for 45 days at either 10 GHz or 50 GHz, and blood cells and serum were then analyzed. The exposed rats showed micronuclei formation and a significant increase in ROS production, along with significant changes in glutathione peroxidase, superoxide dismutase, and catalase levels. The researchers concluded that microwave exposure may be effective at the genetic level and suggested this may indicate tumor promotion through overproduction of reactive oxygen species.
Why This Matters
The rats used were 70 days old and received exposures 2 hours per day for 45 continuous days. The 10 GHz exposure had a power density of 0.214 mW/cm2 and a SAR of 0.014 W/kg, while the 50 GHz exposure had a power density of 0.86 microW/cm2 and a SAR of 8.0 x10(-4) W/kg. Micronuclei formation alongside elevated reactive oxygen species was observed in the exposed animals. The researchers described the antioxidant enzyme changes alongside their conclusion that microwave exposure may be an indication of tumor promotion through the overproduction of reactive oxygen species.
Exposure Details
- SAR
- 0.014 W/kg
- Power Density
- 0.214 mW/cm²
- Source/Device
- 10 GHz
- Exposure Duration
- 2h a day for 45 days
Exposure Context
This study used 0.214 mW/cm² for radio frequency:
- 21.4Mx above the Building Biology guideline of 0.1 μW/m²
- 356.7Kx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
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Wistar rats (70 days old) were exposed for 2 h a day for 45 days continuously at 10 GHz [power densi...
These radiations induce micronuclei formation and significant increase in ROS production. Significan...
It is concluded that microwave exposure can be affective at genetic level. This may be an indication of tumor promotion, which comes through the overproduction of reactive oxygen species.
Show BibTeX
@article{s_2010_evaluation_of_genotoxic_effects_9,
author = {Kumar S and Kesari KK and Behari J.},
title = {Evaluation of genotoxic effects in male Wistar rats following microwave exposure.},
year = {2010},
url = {http://imsear.hellis.org/handle/123456789/145011},
}