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Oxidative Stress

Biochemical and pathological changes in the male rat kidney and bladder following exposure to continuous 900-MHz electromagnetic field on postnatal days 22-59.

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Türedi S, Kerimoğlu G, Mercantepe T, Odacı E. · 2017

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One hour daily of cell phone radiation caused kidney and bladder damage in developing rats through oxidative stress.

Plain English Summary

Summary written for general audiences

Turkish researchers exposed young male rats to cell phone frequency radiation (900 MHz) for one hour daily during their developmental period and examined kidney and bladder tissues. They found significant increases in oxidative stress markers and observed cellular damage including tissue degeneration and increased cell death in both organs. The study demonstrates that even brief daily exposure to radiofrequency radiation during development can cause measurable harm to vital organs.

Why This Matters

This research adds to mounting evidence that radiofrequency radiation affects organs throughout the body, not just the brain where most EMF research has focused. The 900 MHz frequency used matches that of many cell phones and wireless devices, making these findings directly relevant to human exposure scenarios. What's particularly concerning is that the damage occurred with just one hour of daily exposure during the rats' developmental period, equivalent to human childhood and adolescence. The study's documentation of oxidative stress provides a clear biological mechanism for how RF radiation causes cellular harm. The reality is that children today face far more extensive wireless exposure than the limited experimental conditions in this study, raising serious questions about long-term health impacts on developing organs.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900-MHz Duration: 1 h a day on postnatal days 22–59, inclusive

Study Details

To investigate the effect on male rat kidney and bladder tissues of exposure to 900-megahertz (MHz) electromagnetic field (EMF) applied on postnatal days 22–59, inclusive

Twenty-four male Sprague Dawley rats, aged 21 days, were used. These were divided equally into one o...

The findings showed that tissue malondialdehyde increased in EMFG compared to CG and SG in both kidn...

We conclude that continuous exposure to the effect of 900-MHz EMF for 1 h a day on postnatal days 22–59, inclusive, causes an increase in oxidative stress and various pathological changes in male rat kidney and bladder tissues.

Cite This Study
Türedi S, Kerimoğlu G, Mercantepe T, Odacı E. (2017). Biochemical and pathological changes in the male rat kidney and bladder following exposure to continuous 900-MHz electromagnetic field on postnatal days 22-59. Int J Radiat Biol. 93(9):990-999, 2017.
Show BibTeX
@article{s_2017_biochemical_and_pathological_changes_1715,
  author = {Türedi S and Kerimoğlu G and Mercantepe T and Odacı E.},
  title = {Biochemical and pathological changes in the male rat kidney and bladder following exposure to continuous 900-MHz electromagnetic field on postnatal days 22-59.},
  year = {2017},
  doi = {10.1080/09553002.2017.1350768},
  url = {https://www.tandfonline.com/doi/abs/10.1080/09553002.2017.1350768},
}
DOI: 10.1080/09553002.2017.1350768

Cited By (24 papers)

Quick Questions About This Study

Yes, Turkish researchers found that daily one-hour exposure to 900 MHz radiation during development caused significant kidney damage in young male rats. The study observed tissue degeneration, increased cell death, and damage to filtering structures called glomeruli after 38 days of exposure.
Research shows 900 MHz radiation can damage bladder tissue in developing animals. A 2017 study found that one hour daily exposure caused degeneration in bladder lining cells, structural irregularities, and increased cell death in young rats exposed during their growth period.
Just one hour daily of 900 MHz radiation exposure causes measurable oxidative stress in kidney and bladder tissues. The study found increased harmful compounds like malondialdehyde and decreased protective antioxidants like catalase and glutathione after 38 days of exposure.
Yes, even brief daily exposure can cause harm during development. Researchers found that one hour per day of 900 MHz radiation exposure from postnatal days 22-59 caused significant tissue damage and oxidative stress in young rats' kidneys and bladders.
900 MHz radiation causes multiple types of cellular damage including tubule dilation and vacuolization in kidneys, glomerular degeneration, epithelial cell damage in bladders, and increased programmed cell death (apoptosis) in both organs according to microscopic examination of exposed tissues.