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Oxidative Stress

Effect of exposure and withdrawal of 900-MHz-electromagnetic waves on brain, kidney and liver oxidative stress and some biochemical parameters in male rats.

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Ragy MM · 2015

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Cell phone frequency radiation caused organ damage and oxidative stress in rats, but effects reversed when exposure stopped.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to 900-MHz electromagnetic radiation (similar to cell phone frequencies) for one hour daily over 60 days and found significant damage to the brain, liver, and kidneys. The exposure increased harmful oxidative stress markers and damaged tissue function, but these effects reversed when the EMF exposure was stopped for 30 days. This suggests that cell phone radiation may cause measurable biological damage that could potentially be reversed with reduced exposure.

Why This Matters

This study adds to growing evidence that radiofrequency radiation at cell phone frequencies can cause oxidative stress and organ damage, even at relatively short daily exposure periods. What makes this research particularly significant is the recovery phase - the fact that damage markers returned to normal after EMF exposure stopped suggests the body can repair itself when given the opportunity. The 900-MHz frequency used matches GSM cell phone networks, making these findings directly relevant to everyday mobile phone use. While we don't know the exact power levels used in this study, the one-hour daily exposure duration is actually less than what many people experience through their smartphones, tablets, and wireless devices combined. The reality is that this research demonstrates measurable biological effects from EMF exposure, contradicting industry claims that non-thermal levels are completely safe.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900-MHz Duration: 1 h/d for 60 d

Study Details

Increasing use of mobile phones in daily life with increasing adverse effects of electromagnetic radiation (EMR), emitted from mobile on some physiological processes, cause many concerns about their effects on human health. Therefore, this work was designed to study the effects of exposure to mobile phone emits 900-MHz EMR on the brain, liver and kidney of male albino rats.

Thirty male adult rats were randomly divided into four groups (10 each) as follows: control group (r...

EMR emitted from mobile phone led to a significant increase in malondialdehyde (MDA) levels and sign...

In conclusion, electromagnetic field emitting from mobile phone might produce impairments in some biochemicals changes and oxidative stress in brain, liver and renal tissue of albino rats. These alterations were corrected by withdrawal.

Cite This Study
Ragy MM (2015). Effect of exposure and withdrawal of 900-MHz-electromagnetic waves on brain, kidney and liver oxidative stress and some biochemical parameters in male rats. Electromagn Biol Med. 2015;34(4):279-84.
Show BibTeX
@article{mm_2015_effect_of_exposure_and_2532,
  author = {Ragy MM},
  title = {Effect of exposure and withdrawal of 900-MHz-electromagnetic waves on brain, kidney and liver oxidative stress and some biochemical parameters in male rats.},
  year = {2015},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/24712749/},
}
PubMed: 24712749

Cited By (83 papers)

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Quick Questions About This Study

Yes, a 2015 study found that one hour of daily 900 MHz radiation exposure for 60 days significantly damaged brain, liver, and kidney tissue in rats. The radiation increased harmful oxidative stress markers and impaired organ function, similar to damage patterns seen with cell phone frequencies.
Yes, the damage appears reversible. When researchers stopped the 900 MHz radiation exposure for 30 days, all the harmful biochemical changes and oxidative stress markers returned to normal levels. This suggests that reducing EMF exposure may allow organs to recover from radiation damage.
Yes, 900 MHz radiation significantly increased liver enzymes ALT and AST in exposed rats, indicating liver damage. These elevated enzyme levels suggest impaired liver function from the electromagnetic exposure. The liver enzyme levels returned to normal after stopping the radiation exposure for 30 days.
900 MHz EMF exposure significantly increased kidney damage markers including urea and creatinine levels in rat blood. These elevated levels indicate impaired kidney function from the electromagnetic radiation. The kidney function markers normalized after a 30-day recovery period without EMF exposure.
Sixty days of 900 MHz exposure significantly increased malondialdehyde (MDA), a marker of cellular damage, while decreasing total antioxidant capacity in brain, liver, and kidney tissues. This indicates the radiation overwhelmed the body's natural antioxidant defenses, causing measurable oxidative stress damage.