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Extremely-low-frequency magnetic fields disrupt rhythmic slow activity in rat hippocampal slices

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Bawin SM, Satmary WM, Jones RA, Adey WR, Zimmerman G. · 1996

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ELF magnetic fields at everyday exposure levels can disrupt brain rhythms crucial for memory by interfering with cellular signaling.

Plain English Summary

Summary written for general audiences

Scientists exposed rat brain tissue to extremely low frequency magnetic fields at power line frequencies (1-60 Hz). Fields at 56 and 560 microtesla disrupted normal brain rhythms linked to memory, but only when specific brain chemicals were present. This shows magnetic fields can interfere with brain function.

Why This Matters

This study provides compelling evidence that ELF magnetic fields can directly interfere with brain function at the cellular level. The researchers found disruption of theta rhythms, which are crucial for memory processing, at field strengths of 56 microtesla and above. To put this in perspective, these exposure levels are well within the range you might encounter near household appliances or power lines. What makes this research particularly significant is that it demonstrates a clear biological mechanism: ELF fields appear to affect nitric oxide systems in the brain, which play important roles in neuron communication and brain function. The fact that effects were irreversible and occurred through a specific biochemical pathway suggests this isn't just laboratory noise, but a real biological response that could have implications for cognitive function and neurological health.

Exposure Details

Magnetic Field
0.0056, 0.056 and 0.56 mG
Source/Device
1 or 60 Hz
Exposure Duration
10 min

Exposure Context

This study used 0.0056, 0.056 and 0.56 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.0056, 0.056 and 0.56 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 357,143x higher than this exposure level

Study Details

Our studies sought to determine whether ELF magnetic fields could couple directly with brain tissue and affect neuronal activity in vitro.

We used rat hippocampal slices to study field effects on a specific brain activity known as rhythmic...

Sinusoidal 1 Hz fields at 56 and 560 μT, but not at 5.6 μT, triggered the irreversible destabilizati...

These results suggest that ELF magnetic fields exert a strong influence on NO systems in the brain; therefore, they could modulate the functional state of a variety of neuronal ensembles.

Cite This Study
Bawin SM, Satmary WM, Jones RA, Adey WR, Zimmerman G. (1996). Extremely-low-frequency magnetic fields disrupt rhythmic slow activity in rat hippocampal slices Bioelectromagnetics. 17(5):388-395, 1996.
Show BibTeX
@article{sm_1996_extremelylowfrequency_magnetic_fields_disrupt_322,
  author = {Bawin SM and Satmary WM and Jones RA and Adey WR and Zimmerman G.},
  title = {Extremely-low-frequency magnetic fields disrupt rhythmic slow activity in rat hippocampal slices},
  year = {1996},
  
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1521-186X(1996)17:5%3C388::AID-BEM6%3E3.0.CO;2-%23},
}

Quick Questions About This Study

Scientists exposed rat brain tissue to extremely low frequency magnetic fields at power line frequencies (1-60 Hz). Fields at 56 and 560 microtesla disrupted normal brain rhythms linked to memory, but only when specific brain chemicals were present. This shows magnetic fields can interfere with brain function.