Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload
Maaroufi K, Had-Aissouni L, Melon C, Sakly M, Abdelmelek H, Poucet B, Save E. · 2013
View Original AbstractRats exposed to 900 MHz EMF were impaired in object exploration but not in navigation or working memory, and combined EMF with iron overload did not produce greater deficits.
Plain English Summary
Researchers exposed Long-Evans rats to 900 MHz EMF alone or combined with iron overload and tested them in spatial learning tasks including the Morris water maze, radial-arm maze, and object exploration. EMF-exposed rats were impaired in the object exploration task but not in the navigation or working memory tasks. Combined EMF and iron overload did not produce greater behavioral or neurochemical deficits than EMF alone, and neither treatment caused global oxidative stress.
Why This Matters
The study aimed to test whether combined EMF and iron overload would produce greater cognitive and biochemical effects than either treatment alone. EMF exposure altered monoamine content in several brain areas, primarily the hippocampus. The authors concluded that EMF impacts brain and cognitive processes only in tasks exploiting spontaneous exploratory activity, and there were no synergistic effects with high brain iron.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 1 hour per day for 21 consecutive days
Study Details
The objective of the study was thus to examine whether combined 900 MHz EMF exposure and systemic iron overload produces greater cognitive and brain biochemical effects than each treatment separately.
To examine the hypothesis, Long-Evans rats submitted to 900 MHz exposure or combined 900 MHz EMF and...
Rats exposed to EMF were impaired in the object exploration task but not in the navigation and worki...
These results show that there is an impact of EMF on the brain and cognitive processes but this impact is revealed only in a task exploiting spontaneous exploratory activity. In contrast, there are no synergistic effects between EMF and a high content of iron in the brain.
Show BibTeX
@article{k_2013_spatial_learning_monoamines_and_1561,
author = {Maaroufi K and Had-Aissouni L and Melon C and Sakly M and Abdelmelek H and Poucet B and Save E. },
title = {Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload},
year = {2013},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0166432813006244},
}