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Cancer & Tumors

Effect of radiofrequency radiation exposure on mouse skin tumorigenesis initiated by 7,12-dimethybenz[alpha]anthracene.

No Effects Found

Huang TQ, Lee JS, Kim TH, Pack JK, Jang JJ, Seo JS. · 2005

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RF radiation at cell phone levels showed no tumor-promoting effects in this 19-week mouse skin cancer study.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to radiofrequency radiation at cell phone frequencies (849 MHz and 1,763 MHz) for 19 weeks to test whether RF exposure could promote skin tumor growth in animals already treated with a cancer-causing chemical. No skin tumors developed in any of the RF-exposed groups, while 95% of mice treated with a known tumor promoter developed tumors. This suggests that RF radiation at levels similar to mobile phones does not act as a tumor promoter for skin cancer.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 849 MHz - 1.76 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 849 MHz - 1.76 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 849 MHz-, 1,763 MHz Duration: 2 cycles of 45 min exposure with a 15 min interval each day, 5 days a week for 19 weeks

Study Details

To study if RF radiation has a tumor promoting effect, we exposed mice with skin tumorigenesis initiated by 7,12-dimethybenz[a]anthracene (DMBA) to RF radiation.

Eighty male ICR mice were subjected to a single DMBA application (100 microg/100 microl acetone/mous...

All mice were examined weekly at a macroscopic level. No skin tumors were observed in any groups exc...

No evidence was found that RF radiation serves as a tumor promoter for skin tumors. Our data suggests that 849 MHz and 1,763 MHz RF radiations, similar to those emitted from mobile phones, do not have any promoting effect on skin tumor development in DMBA-initiated mice.

Cite This Study
Huang TQ, Lee JS, Kim TH, Pack JK, Jang JJ, Seo JS. (2005). Effect of radiofrequency radiation exposure on mouse skin tumorigenesis initiated by 7,12-dimethybenz[alpha]anthracene. Int J Radiat Biol. 81(12):861-867, 2005.
Show BibTeX
@article{tq_2005_effect_of_radiofrequency_radiation_3093,
  author = {Huang TQ and Lee JS and Kim TH and Pack JK and Jang JJ and Seo JS.},
  title = {Effect of radiofrequency radiation exposure on mouse skin tumorigenesis initiated by 7,12-dimethybenz[alpha]anthracene.},
  year = {2005},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/16524842/},
}
PubMed: 16524842

Cited By (17 papers)

Quick Questions About This Study

No, 849 MHz radiofrequency radiation does not promote skin cancer growth. A 2005 study exposed mice to 849 MHz and 1,763 MHz radiation for 19 weeks after chemical cancer initiation. No skin tumors developed in RF-exposed groups, while 95% of positive control mice developed tumors.
No, 1,763 MHz radiofrequency radiation cannot cause skin tumors in mice. Researchers found no skin tumors in mice exposed to this frequency for 19 weeks, even after treating them with a cancer-causing chemical. This suggests RF radiation doesn't act as a tumor promoter.
Mice were exposed to cell phone frequencies (849 MHz and 1,763 MHz) for 19 weeks in this skin cancer study. Despite this extended exposure period following chemical cancer initiation with DMBA, no skin tumors developed in any radiofrequency-exposed groups.
DMBA-treated mice exposed to cell phone radiation (849 MHz and 1,763 MHz) developed no skin tumors during 19 weeks of exposure. This contrasts sharply with mice treated with TPA tumor promoter, where 95% developed tumors, indicating RF radiation lacks tumor-promoting effects.
No, cell phone frequencies do not affect PCNA staining in mouse skin tissue. Researchers found no differences in proliferating cell nuclear antigen staining between sham-exposed and RF-exposed groups at 849 MHz and 1,763 MHz, indicating no increased cell proliferation from radiation exposure.