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Absence of a synergistic effect between moderate-power radio-frequency electromagnetic radiation and adriamycin on cell-cycle progression and sister-chromatid exchange.

No Effects Found

Ciaravino V, Meltz ML, Erwin DN · 1991

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Microwave radiation at 33.8 W/kg didn't amplify DNA damage from a toxic cancer drug, but this extreme exposure far exceeds everyday wireless device levels.

Plain English Summary

Summary written for general audiences

Researchers exposed Chinese hamster ovary cells to both microwave radiation (2.45 GHz) and adriamycin, a cancer drug that damages DNA, to see if the radiation would amplify the drug's harmful effects. After two hours of simultaneous exposure at 33.8 W/kg (a relatively high power level), they found no synergistic effect - the radiation didn't make the drug more damaging to cells or increase DNA damage. This suggests that microwave radiation at this level doesn't interact with certain toxic chemicals to create additional cellular harm.

Study Details

In our laboratories we are conducting investigations of potential interactions between radio-frequency electromagnetic radiation (RFR) and chemicals that are toxic by different mechanisms to mammalian cells

The RFR is being tested at frequencies in the microwave range and at different power levels. We repo...

Verified statistically, the data indicate that the RFR did not affect changes in cell progression ca...

Cite This Study
Ciaravino V, Meltz ML, Erwin DN (1991). Absence of a synergistic effect between moderate-power radio-frequency electromagnetic radiation and adriamycin on cell-cycle progression and sister-chromatid exchange. Bioelectromagnetics 12(5):289-298, 1991.
Show BibTeX
@article{v_1991_absence_of_a_synergistic_2981,
  author = {Ciaravino V and Meltz ML and Erwin DN},
  title = {Absence of a synergistic effect between moderate-power radio-frequency electromagnetic radiation and adriamycin on cell-cycle progression and sister-chromatid exchange.},
  year = {1991},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/1759979/},
}

Quick Questions About This Study

Researchers exposed Chinese hamster ovary cells to both microwave radiation (2.45 GHz) and adriamycin, a cancer drug that damages DNA, to see if the radiation would amplify the drug's harmful effects. After two hours of simultaneous exposure at 33.8 W/kg (a relatively high power level), they found no synergistic effect - the radiation didn't make the drug more damaging to cells or increase DNA damage. This suggests that microwave radiation at this level doesn't interact with certain toxic chemicals to create additional cellular harm.