The correlation between the frequency of micronuclei and specific chromosome aberrations in human lymphocytes exposed to microwave radiation in vitro.
Garaj-Vrhovac V, Fucic A, Horvat D · 1992
View Original AbstractHuman lymphocytes exposed to microwave radiation showed significantly higher chromosomal aberrations and higher incidence of micronuclei compared to control samples.
Plain English Summary
Researchers exposed human whole-blood samples to continuous microwave radiation at a frequency of 7.7 GHz, at power densities of 0.5, 10, and 30 mW/cm2, for 10, 30, and 60 minutes. In all experimental conditions, the frequency of all types of chromosomal aberrations was significantly higher than in the control samples, and dicentric and ring chromosomes were detected in the irradiated samples. The results showed a positive correlation between micronuclei and specific chromosomal aberrations, including acentric fragments and dicentric chromosomes. The researchers indicated that microwave radiation causes changes in the genome of somatic human cells and that the applied tests are equally sensitive for the detection of the genotoxicity of microwaves.
Why This Matters
The structural chromosome aberration test and the micronucleus test were comparatively analyzed. A correlation between specific chromosomal aberrations and the incidence of micronuclei after in vitro exposure was observed. The researchers described the applied tests as equally sensitive for the detection of the genotoxicity of microwaves.
Exposure Details
- Power Density
- 0.5, 10 and 30 mW/cm²
- Source/Device
- 7.7 GHz
- Exposure Duration
- 10, 30 and 60 min
Exposure Context
This study used 0.5, 10 and 30 mW/cm² for radio frequency:
- 50Mx above the Building Biology guideline of 0.1 μW/m²
- 833.3Kx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To study the correlation between the frequency of micronuclei and specific chromosome aberrations in human lymphocytes exposed to microwave radiation in vitro.
Human whole-blood samples were exposed to continuous microwave radiation, frequency 7.7 GHz, power d...
In all experimental conditions, the frequency of all types of chromosomal aberrations was significan...
The results of the study indicate that microwave radiation causes changes in the genome of somatic human cells and that the applied tests are equally sensitive for the detection of the genotoxicity of microwaves.
Show BibTeX
@article{v_1992_the_correlation_between_the_55,
author = {Garaj-Vrhovac V and Fucic A and Horvat D},
title = {The correlation between the frequency of micronuclei and specific chromosome aberrations in human lymphocytes exposed to microwave radiation in vitro.},
year = {1992},
url = {http://www.sciencedirect.com/science/article/pii/0165799292900064},
}