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Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields.

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Wu W, Yao K, Wang KJ, Lu DQ, He JL, Xu LH, Sun WJ. · 2008

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Adding electromagnetic noise alongside 1800 MHz mobile phone radiation blocked the rise in reactive oxygen species and DNA damage seen in human lens epithelial cells.

Plain English Summary

Summary written for general audiences

Researchers used the DCFH-DA method and comet assay to detect intracellular reactive oxygen species (ROS) and DNA damage in cultured human lens epithelial cells exposed to 4 W/kg 1800 MHz mobile phone radiation or 2 muT electromagnetic noise, or both, for 24 hours intermittently. 1800 MHz mobile phone radiation at 4 W/kg for 24 hours significantly increased intracellular ROS and DNA damage (P<0.05). When electromagnetic noise was added alongside the mobile phone radiation, ROS levels and DNA damage were not significantly elevated compared to sham exposure (P>0.05).

Why This Matters

ROS were measured using the DCFH-DA fluorescence method, and DNA damage was assessed using the comet assay. The radiation exposure was set at 4 W/kg and the electromagnetic noise at 2 muT, both applied for 24 hours intermittently. The researchers concluded that electromagnetic noise can block intracellular ROS production and DNA damage induced by 1800 MHz mobile phone radiation in human lens epithelial cells.

Exposure Details

Magnetic Field
0.002 mT
SAR
4 W/kg
Source/Device
1800 MHz mobile phones and noise magnetic fields
Exposure Duration
24h

Exposure Context

This study used 0.002 mT for magnetic fields:

This study used 4 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.002 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 100 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

To investigate whether the exposure to the electromagnetic noise can block reactive oxygen species (ROS) production and DNA damage of lens epithelial cells induced by 1800 MHz mobile phone radiation.

The DCFH-DA method and comet assay were used respectively to detect the intracellular ROS and DNA da...

1800 MHz mobile phone radiation at 4 W/kg for 24 h increased intracellular ROS and DNA damage signif...

Electromagnetic noise can block intracellular ROS production and DNA damage of human lens epithelial cells induced by 1800 MHz mobile phone radiation.

Cite This Study
Wu W, Yao K, Wang KJ, Lu DQ, He JL, Xu LH, Sun WJ. (2008). Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields. Zhejiang Da XueXueBao Yi Xue Ban 37:34-38, 2008.
Show BibTeX
@article{w_2008_blocking_1800_mhz_mobile_21,
  author = {Wu W and Yao K and Wang KJ and Lu DQ and He JL and Xu LH and Sun WJ.},
  title = {Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields.},
  year = {2008},
  
  url = {http://www.ncbi.nlm.nih.gov/pubmed/18275117},
}
PubMed: 18275117

Cited By (24 papers)

Quick Questions About This Study

The experiments used cultured human lens epithelial cells.
1800 MHz mobile phone radiation at 4 W/kg for 24 hours significantly increased intracellular ROS and DNA damage (P<0.05).
ROS levels and DNA damage were not significantly elevated compared to sham exposure when electromagnetic noise was combined with mobile phone radiation (P>0.05).
DNA damage was detected using the comet assay.
The electromagnetic noise used was 2 muT, applied for 24 hours intermittently.