Using medaka embryos as a model system to study biological effects of the electromagnetic fields on development and behavior
Lee W, Yang KL · 2014
View Original AbstractMedaka fish embryos exposed to electromagnetic fields developed faster and, at the highest level tested, showed heightened anxiety-like behavior.
Plain English Summary
Researchers used medaka fish embryos (Oryzias latipes) to study how electromagnetic fields affect development and behavior. Newly fertilized embryos were randomly assigned to groups exposed to an EMF at 3.2 kHz at intensities of 0.12, 15, 25, or 60 µT, with the 0.12 µT group serving as the control. Embryos exposed to all three EMF levels developed significantly faster across several endpoints, including somite number, eye dimensions, eye pigmentation density, midbrain width, head growth, and day to hatch. The group exposed to 60 µT showed significantly higher levels of anxiety-like behavior than the other groups.
Why This Matters
The embryos were exposed continually until hatch and observed daily, with images recorded to analyze developmental endpoints. Four days after hatching, the hatchlings were tested with a white preference test to measure anxiety-like behavior. The researchers concluded that the EMF tested accelerated embryonic development and heightened anxiety-like behavior. The study also concluded that the medaka embryo is a sensitive and cost-efficient in vivo model system for studying the developmental toxicity of EMFs.
Exposure Details
- Magnetic Field
- 0.00012, 0.015 ,0.025 ,0.06 mT
- Source/Device
- 3.2 kHz
- Exposure Duration
- Continuously during embryonic development of medakas
Exposure Context
This study used 0.00012, 0.015 ,0.025 ,0.06 mT for magnetic fields:
- 6x above the Building Biology guideline of 0.2 mG
- 1.2x above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To study biological effects of the electromagnetic fields on development and behavior using medaka embryos as a model system
Medaka embryos (Oryzias latipes) have been a useful tool to study developmental toxicity in vivo due...
The results showed that embryos exposed to all three levels of the EMF developed significantly faste...
In conclusion, the EMF tested in this study accelerated embryonic development and heightened anxiety-like behavior. Our results also demonstrate that the medaka embryo is a sensitive and cost-efficient in vivo model system to study developmental toxicity of EMFs.
Show BibTeX
@article{w_2014_using_medaka_embryos_as_121,
author = {Lee W and Yang KL},
title = {Using medaka embryos as a model system to study biological effects of the electromagnetic fields on development and behavior},
year = {2014},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0147651314002917},
}