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Chronic electromagnetic field exposure decreases HSP70 levels and lowers cytoprotection.

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Di Carlo A, White N, Guo F, Garrett P, Litovitz T. · 2002

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Chronic EMF exposure reduced cellular protection by 27%, potentially explaining how daily device use could increase disease vulnerability.

Plain English Summary

Summary written for general audiences

Researchers exposed chick embryos to electromagnetic fields (both extremely low frequency and radio frequency) for 4 days and found that chronic exposure reduced levels of HSP70, a protective protein that helps cells survive stress. The EMF exposure made the embryos 27% less able to protect themselves against cellular damage. This suggests that daily EMF exposure, like what mobile phone users experience, could weaken the body's natural defense systems and potentially increase disease risk.

Why This Matters

This study reveals a concerning mechanism by which chronic EMF exposure may compromise our cellular defenses. HSP70 proteins act like molecular bodyguards, protecting cells during stress and helping prevent cancer and other diseases. The 27% reduction in these protective proteins after just 4 days of exposure at 8 microT is particularly troubling when you consider that many household appliances and power lines produce similar or higher magnetic field levels. The researchers specifically noted that the exposure patterns mimicked what mobile phone users experience daily. What makes this research especially significant is that it demonstrates how the body's response to EMF changes over time. While short-term exposure might trigger protective responses, chronic exposure appears to exhaust these defenses, leaving cells more vulnerable to damage. This finding adds important context to the growing body of research linking long-term EMF exposure to increased disease risk.

Exposure Details

Magnetic Field
0.008 mG
Exposure Duration
Continuously for 4 days, or repeated daily (20, 30, or 60 min once or twice daily for 4 days)

Exposure Context

This study used 0.008 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.008 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 250,000x higher than this exposure level

Study Details

Experiments presented in the current report are based on a study in which long-term (4 days), continuous exposure to ELF-EMFs decreased protection against ultraviolet radiation. Based on this result, it was hypothesized that de-protection against hypoxia should also occur following long-term, continuous, or daily, repeated exposures to EMFs.

To test this hypothesis, chick embryos were exposed to ELF-EMFs (8 microT) continuously for 4 days, ...

Several of the exposure protocols yielded embryos that had statistically significant decreases in pr...

Cite This Study
Di Carlo A, White N, Guo F, Garrett P, Litovitz T. (2002). Chronic electromagnetic field exposure decreases HSP70 levels and lowers cytoprotection. J. Cell. Biochem. 84: 447-454, 2002.
Show BibTeX
@article{a_2002_chronic_electromagnetic_field_exposure_946,
  author = {Di Carlo A and White N and Guo F and Garrett P and Litovitz T.},
  title = {Chronic electromagnetic field exposure decreases HSP70 levels and lowers cytoprotection.},
  year = {2002},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/11813250/},
}

Quick Questions About This Study

Researchers exposed chick embryos to electromagnetic fields (both extremely low frequency and radio frequency) for 4 days and found that chronic exposure reduced levels of HSP70, a protective protein that helps cells survive stress. The EMF exposure made the embryos 27% less able to protect themselves against cellular damage. This suggests that daily EMF exposure, like what mobile phone users experience, could weaken the body's natural defense systems and potentially increase disease risk.