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Effect of Exposure to 900 MHz Radiofrequency Radiation on Intrachromosomal Recombination in pKZ1 Mice.

No Effects Found

Sykes PJ, McCallum BD, Bangay MJ, Hooker AM, Morley AA · 2001

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This study found that 25 days of cell phone-level RF radiation altered DNA repair processes in mice, suggesting biological effects beyond direct damage.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to 900 MHz radiofrequency radiation (similar to cell phones) for up to 25 days to see if it affected DNA recombination in spleen cells. They found no effects after short exposures, but after 25 days of exposure, DNA recombination actually decreased below normal levels. While this wasn't the DNA damage scientists typically look for, it suggests RF radiation can alter how cells repair their DNA, though the health significance of this change remains unknown.

Study Details

Radiofrequency (RF) radiation emitted from mobile phones is not considered to be directly genotoxic, but it may have downstream effects on cellular DNA. We studied the effect of 4 W/kg pulsed 900 MHz RF radiation on somatic intrachromosomal recombination in the spleen in the pKZ1 recombination mutagenesis model.

Somatic intrachromosomal recombination inversion events were detected in spleen tissue of pKZ1 mice ...

Cite This Study
Sykes PJ, McCallum BD, Bangay MJ, Hooker AM, Morley AA (2001). Effect of Exposure to 900 MHz Radiofrequency Radiation on Intrachromosomal Recombination in pKZ1 Mice. Radiat Res 156(5):495-502, 2001.
Show BibTeX
@article{pj_2001_effect_of_exposure_to_3433,
  author = {Sykes PJ and McCallum BD and Bangay MJ and Hooker AM and Morley AA},
  title = {Effect of Exposure to 900 MHz Radiofrequency Radiation on Intrachromosomal Recombination in pKZ1 Mice.},
  year = {2001},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/11604062/},
}

Quick Questions About This Study

Researchers exposed mice to 900 MHz radiofrequency radiation (similar to cell phones) for up to 25 days to see if it affected DNA recombination in spleen cells. They found no effects after short exposures, but after 25 days of exposure, DNA recombination actually decreased below normal levels. While this wasn't the DNA damage scientists typically look for, it suggests RF radiation can alter how cells repair their DNA, though the health significance of this change remains unknown.