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Whole body exposure with GSM 900 MHz affects spatial memory in mice

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Fragopoulou AF, Miltiadous P, Stamatakis A, Stylianopoulou F, Koussoulakos SL, Margaritis LH · 2010

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Cell phone radiation impaired spatial memory in mice at exposure levels similar to typical phone use after just four days.

Plain English Summary

Summary written for general audiences

Greek researchers exposed mice to cell phone radiation (900 MHz) for 2 hours daily over 4 days. The exposed mice showed significant deficits in learning and remembering spatial information compared to unexposed mice, suggesting cell phone radiation may impair brain memory functions.

Why This Matters

This study provides compelling evidence that cell phone radiation can directly impair cognitive function, specifically the type of spatial memory processing that occurs in the hippocampus. The SAR levels used (0.41 to 0.98 W/kg) are well within the range of typical cell phone emissions, making these findings directly relevant to human exposure. What makes this research particularly significant is that it demonstrates measurable cognitive effects after just 4 days of 2-hour exposures, a relatively brief exposure period compared to the years of daily use most people accumulate. The fact that the mice showed both learning deficits and memory consolidation problems suggests the radiation may be interfering with fundamental brain processes. While we can't directly extrapolate from mouse studies to humans, this research adds to a growing body of evidence suggesting that the electromagnetic fields from wireless devices may affect brain function in ways we're only beginning to understand.

Exposure Details

SAR
0.41 to 0.98 W/kg
Power Density
0.05 and 0.2 µW/m²
Electric Field
23 and 36 V/m
Source/Device
900 MHz GSM mobile phone
Exposure Duration
2 h daily for 4 days

Exposure Context

This study used 0.05 and 0.2 µW/m² for radio frequency:

This study used 23 and 36 V/m for electric fields:

This study used 0.41 to 0.98 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.05 and 0.2 µW/m²Extreme Concern1,000 uW/m2FCC Limit10M uW/m2Effects observed in the No Concern range (Building Biology)FCC limit is 200,000,000x higher than this exposure level

Study Details

The present work has been designed in order to test the effects of mobile phone radiation on spatial learning and memory in mice Mus musculus Balb/c using the Morris water maze (a hippocampal-dependent spatial memory task), since there is just one other study on mice with very low SAR level (0.05 W/kg) showing no effects.

We have applied a 2 h daily dose of pulsed GSM 900 MHz radiation from commercially available mobile ...

Statistical analysis revealed that during learning, exposed animals showed a deficit in transferring...

Our results provide a basis for more thorough investigations considering reports on non-thermal effects of electromagnetic fields (EMFs).

Cite This Study
Fragopoulou AF, Miltiadous P, Stamatakis A, Stylianopoulou F, Koussoulakos SL, Margaritis LH (2010). Whole body exposure with GSM 900 MHz affects spatial memory in mice Pathophysiology. 17(3):179-187, 2010.
Show BibTeX
@article{af_2010_whole_body_exposure_with_99,
  author = {Fragopoulou AF and Miltiadous P and Stamatakis A and Stylianopoulou F and Koussoulakos SL and Margaritis LH},
  title = {Whole body exposure with GSM 900 MHz affects spatial memory in mice},
  year = {2010},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0928468009001217},
}

Quick Questions About This Study

Greek researchers exposed mice to cell phone radiation (900 MHz) for 2 hours daily over 4 days. The exposed mice showed significant deficits in learning and remembering spatial information compared to unexposed mice, suggesting cell phone radiation may impair brain memory functions.