Brain proteome response following whole body exposure of mice to mobile phone or wireless DECT base radiation
Fragopoulou AF, Samara A, Antonelou MH, Xanthopoulou A, Papadopoulou A, Vougas K, Koutsogiannopoulou E, Anastasiadou E, Stravopodis DJ, Tsangaris GT, Margaritis LH · 2012
View Original AbstractLong-term mobile phone radiation exposure dramatically altered 143 brain proteins in mice, potentially explaining headaches and memory problems in humans.
Plain English Summary
Researchers exposed mice to mobile phone and cordless phone radiation for 8 months and examined brain tissue for protein changes. They found that both radiation sources significantly altered 143 different proteins in brain regions, including proteins involved in brain function, stress response, and cell structure. These protein changes may explain symptoms like headaches, memory problems, and sleep disturbances reported by people with long-term phone use.
Why This Matters
This study provides compelling biological evidence for how wireless radiation affects the brain at the molecular level. The researchers found dramatic protein changes - some proteins decreased by 99.7% while others increased by 114-fold - across multiple brain regions after exposure to radiation levels similar to what you experience during phone calls (SAR 0.17-0.37 W/kg). What makes this research particularly significant is that it examined two different wireless technologies and found similar effects from both, suggesting these aren't isolated findings. The altered proteins include those critical for brain function, stress response, and cellular repair, potentially explaining why epidemiological studies consistently link long-term phone use to headaches, sleep problems, and cognitive issues. This adds to a growing body of research showing that wireless radiation creates measurable biological changes in the brain, even at exposure levels regulators consider 'safe.'
Exposure Details
- SAR
- 0.17 to 0.37 W/kg
- Electric Field
- 15 and 22 V/m
- Source/Device
- 900 MHz Mobile phone
- Exposure Duration
- 3 h daily for 8 months
Exposure Context
This study used 15 and 22 V/m for electric fields:
- 50x above the Building Biology guideline of 0.3 V/m
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The objective of this study was to investigate the effects of two sources of electromagnetic fields (EMFs) on the proteome of cerebellum, hippocampus, and frontal lobe in Balb/c mice following long-term whole body irradiation.
Three equally divided groups of animals (6 animals/group) were used; the first group was exposed to ...
Comparative proteomics analysis revealed that long-term irradiation from both EMF sources altered si...
Show BibTeX
@article{af_2012_brain_proteome_response_following_100,
author = {Fragopoulou AF and Samara A and Antonelou MH and Xanthopoulou A and Papadopoulou A and Vougas K and Koutsogiannopoulou E and Anastasiadou E and Stravopodis DJ and Tsangaris GT and Margaritis LH},
title = {Brain proteome response following whole body exposure of mice to mobile phone or wireless DECT base radiation},
year = {2012},
doi = {10.3109/15368378.2011.631068},
url = {https://www.tandfonline.com/doi/abs/10.3109/15368378.2011.631068},
}