The Static Magnetic Field Remotely Boosts the Efficiency of Doxorubicin through Modulating ROS Behaviors
Hajipour Verdom B, Abdolmaleki P, Behmanesh M. · 2018
View Original AbstractStatic magnetic fields at 10 millitesla enhanced chemotherapy effectiveness by disrupting cellular iron balance and increasing oxidative stress in cancer cells.
Plain English Summary
Researchers studied how static magnetic fields affect cancer treatment with doxorubicin (a common chemotherapy drug). They found that magnetic fields at 10 millitesla enhanced the drug's cancer-killing effects by increasing harmful molecules called reactive oxygen species (ROS) in cancer cells. This could potentially allow doctors to use lower doses of chemotherapy while maintaining effectiveness, reducing side effects for patients.
Why This Matters
This research reveals an intriguing intersection between EMF exposure and cancer treatment that deserves attention. The study demonstrates that static magnetic fields at 10 millitesla can amplify the effectiveness of doxorubicin by disrupting cellular iron balance and boosting oxidative stress in cancer cells. What makes this particularly relevant is the exposure level: 10 millitesla is roughly 200 times stronger than Earth's magnetic field but well within the range of therapeutic magnetic devices and some industrial equipment. The science demonstrates that magnetic fields can fundamentally alter cellular chemistry in ways that affect drug metabolism and cellular vulnerability. While this specific application shows potential therapeutic benefits, it underscores a broader reality about EMF bioeffects that the wireless industry often dismisses. If magnetic fields can enhance chemotherapy drugs by modulating cellular processes like iron homeostasis and ROS generation, this confirms that EMF exposure produces measurable biological changes at the cellular level. You don't have to be undergoing cancer treatment to recognize the implications: our cells respond to magnetic field exposure in complex, measurable ways.
Exposure Details
- Magnetic Field
- 5, 10, 15 and 20 mG
- Exposure Duration
- 24 and 48 h
Exposure Context
This study used 5, 10, 15 and 20 mG for magnetic fields:
- 250Kx above the Building Biology guideline of 0.2 mG
- 50Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
Here, we investigated the potential effects of homogenous static magnetic field (SMF) on DOXO-induced toxicity and proliferation rate of cancer cells.
The results indicated that SMF similar to DOXO decreased the cell viability as well as the prolifera...
In conclusion, these findings suggest that SMF can decrease required dose of chemotherapy drugs such as DOXO and thereby decrease their side effect.
Show BibTeX
@article{b_2018_the_static_magnetic_field_382,
author = {Hajipour Verdom B and Abdolmaleki P and Behmanesh M.},
title = {The Static Magnetic Field Remotely Boosts the Efficiency of Doxorubicin through Modulating ROS Behaviors},
year = {2018},
url = {https://www.nature.com/articles/s41598-018-19247-8},
}