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Developmental toxicity interactions of salicylic acid and radiofrequency radiation or 2-methoxyethanol in rats.

No Effects Found

Nelson BK, Snyder DL, Shaw PB · 1999

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RF radiation didn't enhance birth defects from salicylic acid in rats, suggesting chemical-RF interactions are substance-specific rather than universal.

Plain English Summary

Summary written for general audiences

Researchers exposed pregnant rats to radiofrequency radiation combined with salicylic acid (aspirin-like compound) to see if RF radiation would worsen birth defects caused by the chemical. Unlike previous studies with other chemicals, they found no evidence that RF radiation made salicylic acid more harmful to developing fetuses. This suggests that RF radiation's ability to enhance chemical toxicity may depend on the specific chemical involved.

Study Details

The purpose of the present research was to determine if the synergistic effects noted for RF radiation and 2ME are generalizable to other chemicals.

Since salicylic acid (SA) is widely used as an analgesic and is teratogenic in animals, SA was sele...

The data provide no evidence of synergistic interactions between RF radiation and salicylic acid (re...

This investigation highlights the importance of additional research on interactions in developmental toxicology, and emphasizes the need to consider combined exposure effects when developing both physical agent and chemical agent exposure guidelines and intervention strategies.

Cite This Study
Nelson BK, Snyder DL, Shaw PB (1999). Developmental toxicity interactions of salicylic acid and radiofrequency radiation or 2-methoxyethanol in rats. Reprod Toxicol 13(2):137-145, 1999.
Show BibTeX
@article{bk_1999_developmental_toxicity_interactions_of_3271,
  author = {Nelson BK and Snyder DL and Shaw PB},
  title = {Developmental toxicity interactions of salicylic acid and radiofrequency radiation or 2-methoxyethanol in rats.},
  year = {1999},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/10213521/},
}

Quick Questions About This Study

Researchers exposed pregnant rats to radiofrequency radiation combined with salicylic acid (aspirin-like compound) to see if RF radiation would worsen birth defects caused by the chemical. Unlike previous studies with other chemicals, they found no evidence that RF radiation made salicylic acid more harmful to developing fetuses. This suggests that RF radiation's ability to enhance chemical toxicity may depend on the specific chemical involved.