Behavioural profile of Wistar rats with unilateral striatal lesion by quinolinic acid (animal model of Huntington disease) post-injection of apomorphine and exposure to static magnetic field.
Giorgetto C, Silva EC, Kitabatake TT, Bertolino G, de Araujo JE. · 2015
View Original AbstractStatic magnetic fields at 3,200 Gauss protected brain neurons and improved motor function in rats with brain lesions.
Plain English Summary
Researchers exposed rats with brain lesions (modeling Huntington's disease) to 3,200 Gauss static magnetic fields for seven days. Magnetic field exposure preserved brain neurons and improved movement compared to untreated rats, suggesting static magnetic fields may help brain healing in neurological conditions.
Why This Matters
This study reveals something remarkable: static magnetic fields at 3,200 Gauss (320 millitesla) appeared to protect brain neurons and improve motor function in rats with brain lesions. What makes this particularly significant is the exposure level - 3,200 Gauss is roughly 64,000 times stronger than Earth's natural magnetic field, yet still within the range of some medical MRI machines and certain industrial applications. The research demonstrates that magnetic fields can have measurable biological effects on brain tissue and behavior, adding to the growing body of evidence that electromagnetic fields interact with biological systems in ways we're still discovering. While this was a therapeutic application rather than an adverse effect study, it underscores the reality that magnetic fields are not biologically inert - they can influence cellular processes, neuronal survival, and brain function in measurable ways.
Exposure Details
- Magnetic Field
- 320 mG
- Exposure Duration
- 7 days
Exposure Context
This study used 320 mG for magnetic fields:
- 16Mx above the Building Biology guideline of 0.2 mG
- 3.2Mx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The aim of this study is to observe Behavioural profile of Wistar rats with unilateral striatal lesion by quinolinic acid (animal model of Huntington disease) post-injection of apomorphine and exposure to static magnetic field
We analysed the motor behaviour of Wistar rats after 7 days lesion in the left striatum, injected wi...
In the activity cage test for distance (F = 3.19), time of activity (F = 5.46) and crossings (F = 3....
Thus, the results suggest that the static magnetic field north and south promoted a distinct behavioural profile and morphological preservation after 7 days of lesion with quinolinic acid associated with APO.
Show BibTeX
@article{c_2015_behavioural_profile_of_wistar_647,
author = {Giorgetto C and Silva EC and Kitabatake TT and Bertolino G and de Araujo JE.},
title = {Behavioural profile of Wistar rats with unilateral striatal lesion by quinolinic acid (animal model of Huntington disease) post-injection of apomorphine and exposure to static magnetic field.},
year = {2015},
url = {https://pubmed.ncbi.nlm.nih.gov/25665872/},
}