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Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus.

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Amara S, Douki T, Garrel C, Favier A, Ben Rhouma K, Sakly M, Abdelmelek H. · 2011

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Static magnetic fields worsened cadmium's toxic brain effects, suggesting EMF exposure may increase vulnerability to other environmental toxins.

Plain English Summary

Summary written for general audiences

Scientists exposed rats to static magnetic fields for 30 days, both alone and with cadmium toxin. Magnetic field exposure worsened cadmium's harmful brain effects, increasing cellular damage and reducing protective antioxidants. This suggests magnetic fields may make brains more vulnerable to environmental toxins.

Why This Matters

This study reveals a concerning interaction effect that deserves attention in our increasingly EMF-saturated world. While the 128 mT exposure level is significantly higher than typical household magnetic field exposures (which range from 0.01-1 mT), the research demonstrates that magnetic fields can amplify the harmful effects of other environmental toxins on brain tissue. The science shows that magnetic field exposure reduced the brain's natural antioxidant defenses and increased markers of cellular damage when combined with cadmium - a heavy metal we encounter through air pollution, cigarette smoke, and contaminated foods. What this means for you is that EMF exposure may not just pose direct health risks, but could also make your body more susceptible to other environmental hazards. This synergistic effect represents an understudied dimension of EMF health impacts that regulatory agencies have yet to adequately address.

Exposure Details

Magnetic Field
128 mG
Exposure Duration
1 hour/day for 30 consecutive days

Exposure Context

This study used 128 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 128 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 16x higher than this exposure level

Study Details

The present study was undertaken to determine the effect of co-exposure to static magnetic field (SMF) and cadmium (Cd) on the antioxidant enzymes activity and DNA integrity in rat brain.

Sub-chronic exposure to CdCl (CdCl(2), 40 mg/L, per os) for 30 days

Sub-chronic exposure to CdCl (CdCl(2), 40 mg/L, per os) for 30 days resulted in a significant reduct...

Our data showed that Cd exposure altered the antioxidant enzymes activity and induced oxidative DNA lesions in rat brain. The combined effect of SMF and Cd increased oxidative damage in rat brain as compared with Cd-exposed rats.

Cite This Study
Amara S, Douki T, Garrel C, Favier A, Ben Rhouma K, Sakly M, Abdelmelek H. (2011). Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus. Toxicol Ind Health. 27(2):99-106, 2011.
Show BibTeX
@article{s_2011_effects_of_static_magnetic_596,
  author = {Amara S and Douki T and Garrel C and Favier A and Ben Rhouma K and Sakly M and Abdelmelek H.},
  title = {Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus.},
  year = {2011},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/20837562/},
}

Quick Questions About This Study

Scientists exposed rats to static magnetic fields for 30 days, both alone and with cadmium toxin. Magnetic field exposure worsened cadmium's harmful brain effects, increasing cellular damage and reducing protective antioxidants. This suggests magnetic fields may make brains more vulnerable to environmental toxins.