Clinico-morphological and biochemical changes in experimental microwave cataracts
Grechuskina, V.A. · 1972
Rabbits exposed to medium-intensity microwaves developed cataracts that later regressed, accompanied by reduced ascorbic acid and thiol groups in the lens.
Plain English Summary
Cataracts developed in 23 rabbits, appearing first in the posterior lens suture and later regressing over two to three months. During cataract formation, ascorbic acid and thiol groups in the lens decreased sharply. During regression, ascorbic acid and thiol group levels returned to normal.
Why This Matters
Younger rabbits developed opacity immediately after exposure, while older rabbits showed opacity after 3 to 7 days. Five older rabbits were sacrificed right after exposure to test if biochemical changes precede lens opacity. The cataract grew in a lace-like pattern but did not spread to the equatorial region. Morphological examination revealed homogenization and fiber separation in the posterior lens cortex, while the equatorial region was unaffected. Irreversible iris changes including sphincter hypertrophy and pigment destruction were also observed.
Exposure Information
Specific exposure levels were not quantified in this study. Duration: 15 minutes
Show BibTeX
@article{clinico_morphological_and_biochemical_changes_in_experimental_microwave_cataract_g6051,
author = {Grechuskina and V.A.},
title = {Clinico-morphological and biochemical changes in experimental microwave cataracts},
year = {1972},
}