Comparative of transcranial magnetic stimulation and other treatments in experimental autoimmune encephalomyelitis
Medina-Fernandez FJ, Escribano BM, Luque E, Caballero-Villarraso J, Gomez-Chaparro JL, Feijoo M, Garcia-Maceira FI, Pascual-Leone A, Drucker-Colin R, Tunez I · 2018
View Original AbstractControlled magnetic field therapy at 0.7 mT showed stronger neuroprotective effects than pharmaceutical treatments in this multiple sclerosis model.
Plain English Summary
Researchers tested whether transcranial magnetic stimulation (TMS) using 60 Hz magnetic fields at 0.7 mT could help treat an animal model of multiple sclerosis. They found that TMS reduced brain inflammation and oxidative stress (cellular damage from unstable molecules) more effectively than standard pharmaceutical treatments. This suggests magnetic field therapy might have protective effects on the nervous system.
Why This Matters
This study presents an intriguing paradox in EMF research. While much of our database documents harmful effects from electromagnetic field exposure, this research shows therapeutic benefits from targeted magnetic field application at 60 Hz and 0.7 mT. The exposure level is roughly 700 times stronger than typical household magnetic field exposure (around 1 µT), representing intentional medical-grade stimulation rather than incidental environmental exposure. What makes this particularly significant is that TMS outperformed established pharmaceutical treatments for neuroinflammation, suggesting that under controlled conditions, specific EMF parameters might offer genuine medical benefits. However, this doesn't contradict concerns about chronic, uncontrolled EMF exposure from everyday sources. The key difference lies in dosage, duration, and therapeutic intent versus involuntary environmental exposure.
Exposure Details
- Magnetic Field
- 0.7 mG
- Source/Device
- 60 Hz
Exposure Context
This study used 0.7 mG for magnetic fields:
- 35Kx above the Building Biology guideline of 0.2 mG
- 7Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The effects of transcranial magnetic stimulation (TMS), natalizumab (nata), dimethyl fumarate (DMF) and dexamethasone (DEX) on clinical score and oxidative stress produced by a single dose of myelin oligodendrocyte glycoprotein (MOG) in tail of Dark Agouti rats was studied.
TMS (60 Hz and 0.7 mT), nata (5 mg/kg), DMF (15 mg/kg) and DEX (300 μg/kg) was applied for 21 after ...
MOG triggered significant increase in clinical score and in the levels of lipid peroxides and carbon...
These results support the antioxidant and neuroprotective action of TMS, as well as an activity higher than other clinical treatments.
Show BibTeX
@article{fj_2018_comparative_of_transcranial_magnetic_426,
author = {Medina-Fernandez FJ and Escribano BM and Luque E and Caballero-Villarraso J and Gomez-Chaparro JL and Feijoo M and Garcia-Maceira FI and Pascual-Leone A and Drucker-Colin R and Tunez I},
title = {Comparative of transcranial magnetic stimulation and other treatments in experimental autoimmune encephalomyelitis},
year = {2018},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0361923017305786},
}