Extremely low frequency magnetic field modulates the level of neurotransmitters.
Chung YH, Lee YJ, Lee HS, Chung SJ, Lim CH, Oh KW, Sohn UD, Park ES, Jeong JH · 2015
View Original AbstractExposure to a 60 Hz, 2.0 mT extremely low frequency magnetic field produced significant differences in multiple neurotransmitters across rat brain regions.
Plain English Summary
Researchers exposed rats to an extremely low frequency magnetic field at 60 Hz and 2.0 mT for 2 or 5 days, then measured neurotransmitter levels in the cortex, striatum, thalamus, cerebellum and hippocampus. The exposure produced significant differences in norepinephrine and vanillyl mandelic acid in the striatum, thalamus, cerebellum and hippocampus. Significant increases in serotonin and 5-hydroxyindoleacetic acid were observed in the striatum, thalamus or hippocampus, and dopamine concentration was significantly increased in the thalamus. The researchers concluded that exposure to ELF-MF may evoke changes in these brain chemicals, though the mechanisms remain to be characterized.
Why This Matters
The study aimed to observe whether extremely low frequency magnetic fields may be relevant to changes of major neurotransmitters in rat brain. Brain areas examined included the cortex, striatum, thalamus, cerebellum and hippocampus. ELF-MF tended to increase levels of amino acid neurotransmitters such as glutamine, glycine and γ-aminobutyric acid in the striatum and thalamus, whereas it decreased the levels in the cortex, cerebellum and hippocampus. ELF-MF significantly increased nitric oxide concentration in the striatum, thalamus and hippocampus. The researchers noted that the extent and property of these changes vary with the brain areas.
Exposure Details
- Magnetic Field
- 2 mT
- Source/Device
- 60 Hz
- Exposure Duration
- 2 or 5 days
Exposure Context
This study used 2 mT for magnetic fields:
- 100Kx above the Building Biology guideline of 0.2 mG
- 20Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
This study was aimed to observe that extremely low frequency magnetic field (ELF-MF) may be relevant to changes of major neurotransmitters in rat brain.
After the exposure to ELF-MF (60 Hz, 2.0 mT) for 2 or 5 days, we measured the levels of biogenic ami...
The exposure of ELF-MF for 2 or 5 days produced significant differences in norepinephrine and vanill...
The present study has demonstrated that exposure to ELF-MFs may evoke the changes in the levels of biogenic amines, amino acid and NO in the brain although the extent and property vary with the brain areas. However, the mechanisms remain further to be characterized.
Show BibTeX
@article{yh_2015_extremely_low_frequency_magnetic_332,
author = {Chung YH and Lee YJ and Lee HS and Chung SJ and Lim CH and Oh KW and Sohn UD and Park ES and Jeong JH},
title = {Extremely low frequency magnetic field modulates the level of neurotransmitters.},
year = {2015},
url = {https://synapse.koreamed.org/upload/SynapseData/PDFData/0067KJPP/kjpp-19-15.pdf},
}