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Ouabain inhibition of kidney ATPase is altered by 9.14 GHz radiation.

Bioeffects Seen

Brown HD, Chattopadhyay SK · 1991

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Microwave radiation disrupted kidney enzyme regulation at 20 W/kg SAR, suggesting EMF can interfere with fundamental cellular control mechanisms.

Plain English Summary

Summary written for general audiences

Researchers exposed dog kidney tissue to 9.14 GHz microwave radiation (similar to some radar frequencies) for 5 minutes and found it significantly disrupted how a key enzyme called ATPase functions. The radiation interfered with ouabain, a compound that normally regulates this enzyme, reducing its effectiveness as a control mechanism. This suggests microwave radiation can alter fundamental cellular processes that keep our kidneys working properly.

Why This Matters

This study reveals something concerning about how microwave radiation affects cellular machinery at the molecular level. The researchers found that 9.14 GHz radiation disrupted the normal regulation of Na+/K+-ATPase, an enzyme critical for maintaining proper cellular function in kidneys. What makes this particularly significant is that the radiation interfered with ouabain's ability to regulate this enzyme - essentially breaking a fundamental control mechanism that cells rely on. The 20 W/kg SAR used in this study is higher than typical cell phone exposures (which range from 0.5-2 W/kg), but it's within the range of some industrial and military radar applications. The reality is that this adds to a growing body of evidence showing EMF can disrupt cellular processes in ways we're still discovering. While this was an isolated tissue study, it demonstrates that microwave radiation can interfere with basic cellular functions that are essential for organ health.

Exposure Details

SAR
20 W/kg
Source/Device
9.14 GHz
Exposure Duration
5 minutes

Exposure Context

This study used 20 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 20 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 0x higher than this exposure level

Study Details

The aim of this study is to observe Ouabain inhibition of kidney ATPase is altered by 9.14 GHz radiation.

At each of several stabilized temperatures between 7.0 and 43.8 °C, increases in dog-kidney, Na+ −, ...

However, at 24.9 °C, a 23% decrease occurred. Comparisons of activity of ouabain-inhibited reactions...

Cite This Study
Brown HD, Chattopadhyay SK (1991). Ouabain inhibition of kidney ATPase is altered by 9.14 GHz radiation. Bioelectromagnetics 12(3):137-143, 1991.
Show BibTeX
@article{hd_1991_ouabain_inhibition_of_kidney_879,
  author = {Brown HD and Chattopadhyay SK},
  title = {Ouabain inhibition of kidney ATPase is altered by 9.14 GHz radiation.},
  year = {1991},
  doi = {10.1002/bem.2250120302},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.2250120302},
}

Quick Questions About This Study

Researchers exposed dog kidney tissue to 9.14 GHz microwave radiation (similar to some radar frequencies) for 5 minutes and found it significantly disrupted how a key enzyme called ATPase functions. The radiation interfered with ouabain, a compound that normally regulates this enzyme, reducing its effectiveness as a control mechanism. This suggests microwave radiation can alter fundamental cellular processes that keep our kidneys working properly.