Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells
Authors not listed · 2011
Exposure to 1,763 MHz RF radiation at 10 W/kg induced IGF-1 expression in human dermal papilla cells and enhanced hair shaft elongation in organ cultures.
Plain English Summary
Researchers exposed cultured human dermal papilla cells to 1,763 MHz RF radiation at a specific absorption rate of 10 W/kg. IGF-1 mRNA expression was significantly induced, leading to increased BCL-2 and CCND1 proteins and increased phosphorylation of MAPK1. Exposure for 1 hour per day over 7 days significantly enhanced hair shaft elongation in ex vivo hair organ cultures. In follicular matrix keratinocytes, Ki-67 expression increased and TUNEL signaling decreased. The authors suggest that 1,763 MHz RF exposure stimulates hair growth in vitro through IGF-1 induction in dermal papilla cells.
Why This Matters
The authors noted that RF radiation does not transfer enough energy to break covalent bonds. They suggested that such low-energy stimuli might still induce specific molecular responses.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{induction_of_hair_growth_by_insulin_like_growth_factor_1_in_1763_mhz_radiofrequency_irradiated_hair_follicle_cells_ce737,
author = {Unknown},
title = {Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells},
year = {2011},
doi = {10.1371/journal.pone.0028474},
}