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Microglial activation as a measure of stress in mouse brains exposed acutely (60 minutes) and long-term (2 years) to mobile telephone radiofrequency fields.

No Effects Found

Finnie JW, Cai Z, Manavis J, Helps S, Blumbergs PC. · 2010

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Two years of cell phone radiation exposure showed no brain immune activation in mice, even at levels higher than typical phone use.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to cell phone radiation at 900 MHz for either one hour or repeatedly over two years, then examined their brains for signs of microglial activation (immune cells that respond to brain stress or damage). They found no evidence that either short-term or long-term radiofrequency exposure activated these immune cells, even though the same cells responded strongly when brain tissue was physically damaged. This suggests that cell phone radiation at these levels may not trigger the brain's stress response mechanisms.

Study Details

To determine whether acute or long-term exposure of the brain to mobile telephone radiofrequency (RF) fields produces activation of microglia, which normally respond rapidly to any change in their microenvironment.

Using a purpose designed exposure system at 900 MHz, mice were given a single, far-field whole body ...

There was no increase in microglial Iba1 expression in brains short or long-term exposed to mobile t...

Acute (60 minutes) or longer duration (2 years) exposure of murine brains to mobile telephone RF fields did not produce any microglial activation detectable by Iba1 immunostaining.

Cite This Study
Finnie JW, Cai Z, Manavis J, Helps S, Blumbergs PC. (2010). Microglial activation as a measure of stress in mouse brains exposed acutely (60 minutes) and long-term (2 years) to mobile telephone radiofrequency fields. Pathology. 42(2):151-154, 2010.
Show BibTeX
@article{jw_2010_microglial_activation_as_a_3023,
  author = {Finnie JW and Cai Z and Manavis J and Helps S and Blumbergs PC.},
  title = {Microglial activation as a measure of stress in mouse brains exposed acutely (60 minutes) and long-term (2 years) to mobile telephone radiofrequency fields.},
  year = {2010},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/20085509/},
}

Quick Questions About This Study

Researchers exposed mice to cell phone radiation at 900 MHz for either one hour or repeatedly over two years, then examined their brains for signs of microglial activation (immune cells that respond to brain stress or damage). They found no evidence that either short-term or long-term radiofrequency exposure activated these immune cells, even though the same cells responded strongly when brain tissue was physically damaged. This suggests that cell phone radiation at these levels may not trigger the brain's stress response mechanisms.