Low Frequency Stimulation Reverses the Kindling-Induced Impairment of Learning and Memory in the Rat Passive-avoidance Test.
Esmaeilpour K, Sheibani V, Shabani M, Mirnajafi-Zadeh J, Akbarnejad Z. · 2018
View Original AbstractLow-frequency electrical stimulation at 1 Hz reversed seizure-induced memory loss in rats, showing therapeutic potential for specific EMF applications.
Plain English Summary
Researchers studied whether low-frequency electrical stimulation (1 Hz) could help reverse memory problems caused by seizures in rats. They found that applying brief electrical stimulation treatments after seizures not only restored learning and memory abilities but also protected brain cells from seizure-related damage. This suggests that controlled electrical stimulation might offer a therapeutic approach for treating cognitive problems in epilepsy patients.
Why This Matters
This research reveals something fascinating about how specific electromagnetic frequencies can actually benefit brain function rather than harm it. While most EMF research focuses on potential negative effects from wireless devices and power lines, this study demonstrates that precisely controlled 1 Hz stimulation can reverse seizure-induced cognitive damage and protect neurons. The science demonstrates that frequency matters enormously - the same electrical energy that might be harmful at one frequency can be therapeutic at another. What this means for you is that the EMF story isn't simply 'all electromagnetic fields are bad.' The reality is more nuanced: it's about the specific characteristics of the exposure, including frequency, intensity, and duration. This study adds to growing evidence that certain low-frequency stimulations may have legitimate medical applications, even as we remain concerned about uncontrolled exposures from everyday devices.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 1 Hz Duration: 30 s, 6 h, 24 h, and 30 h
Study Details
The main goal of this research is investigating the possible effect of LFS on seizure-induced cognitive dysfunction.
To this end, the kindled animal were prepared via CA1 electrical stimulation in a semi-rapid way (12...
Hippocampal kindled rats showed deficits in learning and memory when passive avoidance test was perf...
LFS may have some protection against seizure-induced cognitive damage in kindled rats.
Show BibTeX
@article{k_2018_low_frequency_stimulation_reverses_1741,
author = {Esmaeilpour K and Sheibani V and Shabani M and Mirnajafi-Zadeh J and Akbarnejad Z.},
title = {Low Frequency Stimulation Reverses the Kindling-Induced Impairment of Learning and Memory in the Rat Passive-avoidance Test.},
year = {2018},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015633/},
}