Effects of a 300 mT static magnetic field on human umbilical vein endothelial cells.
Potenza L, Martinelli C, Polidori E, Zeppa S, Calcabrini C, Stocchi L, Sestili P, Stocchi V · 2010
View Original AbstractStatic magnetic fields can cause temporary DNA damage and cellular stress, but healthy cells appear capable of recovery and adaptation.
Plain English Summary
Scientists exposed human blood vessel cells to strong magnetic fields for up to 72 hours. The magnetic field initially caused DNA damage and cellular stress within 4 hours, but cells recovered completely by 48 hours, suggesting healthy cells can adapt to magnetic field exposure.
Why This Matters
This study provides important insights into how static magnetic fields affect human cells at the cellular level. The 300 millitesla exposure used here is significantly stronger than what you'd encounter from household appliances or even MRI machines (which typically use 1,500-3,000 millitesla but for much shorter durations). What's particularly noteworthy is the biphasic response the researchers observed - initial cellular damage followed by apparent recovery and adaptation. This pattern suggests that our cells have evolved mechanisms to cope with magnetic field exposure, but it also raises questions about what happens with chronic, lower-level exposures that don't trigger these protective responses. The temporary increase in reactive oxygen species and mitochondrial stress observed in this study aligns with a growing body of research showing that EMF exposure can disrupt cellular energy production, even when cells ultimately survive the exposure.
Exposure Details
- Magnetic Field
- 300 mG
- Exposure Duration
- 4, 24, 48, and 72 h
Exposure Context
This study used 300 mG for magnetic fields:
- 15Mx above the Building Biology guideline of 0.2 mG
- 3Mx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
This study describes the effects of a static magnetic field (SMF) on cell growth and DNA integrity of human umbilical vein endothelial cells (HUVECs).
Fast halo assay was used to investigate nuclear damage; quantitative polymerase chain reaction (QPCR...
Compared to control samples (unexposed cultures) the SMF-exposed cells did not show a statistically ...
The results suggest that a 300 mT SMF does not cause permanent DNA damage in HUVECs and stimulates a transient mitochondrial biogenesis. Bioelectromagnetics 31:630–639, 2010.
Show BibTeX
@article{l_2010_effects_of_a_300_446,
author = {Potenza L and Martinelli C and Polidori E and Zeppa S and Calcabrini C and Stocchi L and Sestili P and Stocchi V},
title = {Effects of a 300 mT static magnetic field on human umbilical vein endothelial cells.},
year = {2010},
doi = {10.1002/bem.20591},
url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.20591},
}