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Extremely low frequency magnetic field induces oxidative stress in mouse cerebellum.

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Chu LY, Lee JH, Nam YS, Lee YJ, Park WH, Lee BC, Kim D, Chung YH, Jeong JH · 2011

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Magnetic field exposure triggered brain cell damage through oxidative stress in mice, revealing a biological mechanism for potential neurological harm.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to 60 Hz magnetic fields (the same frequency as household electricity) for 3 hours and found significant oxidative stress in the cerebellum, the brain region controlling movement and coordination. The magnetic field exposure increased harmful molecules called free radicals while depleting protective antioxidants like vitamin C. This suggests that magnetic fields from power lines and electrical devices may damage brain cells through oxidative stress.

Why This Matters

This study adds important evidence to concerns about magnetic field exposure from our electrical infrastructure. The 2.3 mT exposure level is roughly 2,300 times higher than typical household levels, but it's within the range you might encounter very close to high-voltage power lines or certain industrial equipment. What makes this research particularly significant is that it demonstrates a clear biological mechanism - oxidative stress - by which magnetic fields could harm brain tissue. The cerebellum's vulnerability is especially concerning given its critical role in motor control and balance. While the exposure was acute rather than chronic, the findings align with a growing body of research showing that magnetic fields can trigger cellular damage through free radical production. The reality is that we're all exposed to these fields daily, and while most exposures are much lower than this study used, the demonstrated biological pathway raises legitimate questions about long-term cumulative effects.

Exposure Details

Magnetic Field
2.3 mG
Source/Device
60 Hz
Exposure Duration
3 hours

Exposure Context

This study used 2.3 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 2.3 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Severe Concern range (Building Biology)FCC limit is 870x higher than this exposure level

Study Details

We have investigated whether extremely low frequency magnetic field (ELF-MF) induces lipid peroxidation and reactive oxygen species in mouse cerebellum.

After exposure to 60 Hz ELF-MF at 2.3 mT intensity for 3 hours, there was a significant increase in ...

These results indicate that ELF-MF may induce oxidative stress in mouse cerebellum. However, the mechanism remains further to be characterized.

Cite This Study
Chu LY, Lee JH, Nam YS, Lee YJ, Park WH, Lee BC, Kim D, Chung YH, Jeong JH (2011). Extremely low frequency magnetic field induces oxidative stress in mouse cerebellum. Gen Physiol Biophys. 30(4):415-421, 2011.
Show BibTeX
@article{ly_2011_extremely_low_frequency_magnetic_331,
  author = {Chu LY and Lee JH and Nam YS and Lee YJ and Park WH and Lee BC and Kim D and Chung YH and Jeong JH},
  title = {Extremely low frequency magnetic field induces oxidative stress in mouse cerebellum.},
  year = {2011},
  
  url = {https://europepmc.org/article/med/22131325},
}

Quick Questions About This Study

Researchers exposed mice to 60 Hz magnetic fields (the same frequency as household electricity) for 3 hours and found significant oxidative stress in the cerebellum, the brain region controlling movement and coordination. The magnetic field exposure increased harmful molecules called free radicals while depleting protective antioxidants like vitamin C. This suggests that magnetic fields from power lines and electrical devices may damage brain cells through oxidative stress.