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Neuroprotective effect of weak static magnetic fields in primary neuronal cultures.

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Ben Yakir-Blumkin M, Loboda Y, Schächter L, Finberg JP. · 2014

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Static magnetic fields at 50 gauss protected brain neurons from death by 57%, suggesting some EMF exposures may be beneficial.

Plain English Summary

Summary written for general audiences

Researchers exposed rat brain neurons to weak static magnetic fields (50 gauss) for seven days and found these fields provided significant protection against cell death. The magnetic field exposure reduced neuron death by 57% when cells were exposed to a toxic chemical, and decreased multiple markers of cellular damage by 40-80%. This suggests static magnetic fields might influence brain cell survival through changes in calcium channels.

Why This Matters

This study reveals something fascinating about static magnetic fields and brain health that challenges our typical focus on potential EMF harms. The researchers found that relatively weak static magnetic fields - about 100 times stronger than Earth's natural field but still quite modest - actually protected neurons from dying. What makes this particularly intriguing is the exposure level: 50 gauss is comparable to what you might encounter very close to some household appliances or certain magnetic therapy devices. The protective effect worked through calcium channels, the same cellular pathways that other EMF research has shown can be disrupted by radiofrequency fields. This adds another layer of complexity to our understanding of how different types of electromagnetic fields interact with our biology - some frequencies and field types may harm, while others might help.

Exposure Details

Magnetic Field
5 mG
Exposure Duration
7 days

Exposure Context

This study used 5 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 5 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 400x higher than this exposure level

Study Details

We examine the effect of SMFs on neuronal survival in primary cortical and hippocampal neurons that constitute a suitable experimental system for modeling the neurodegenerative state in vitro.

We show that weak SMF exposure interferes with the apoptotic programing in rat primary cortical and ...

Accompanied by a marked decrease in the expression of the pro-apoptotic markers: cleaved poly ADP ri...

These findings show the potential susceptibility of the CNS to weak SMF exposure and have implications for the design of novel strategies for the treatment and/or prevention of neurodegenerative diseases.

Cite This Study
Ben Yakir-Blumkin M, Loboda Y, Schächter L, Finberg JP. (2014). Neuroprotective effect of weak static magnetic fields in primary neuronal cultures. Neuroscience. 278:313-326, 2014.
Show BibTeX
@article{m_2014_neuroprotective_effect_of_weak_603,
  author = {Ben Yakir-Blumkin M and Loboda Y and Schächter L and Finberg JP.},
  title = {Neuroprotective effect of weak static magnetic fields in primary neuronal cultures.},
  year = {2014},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/25171788/},
}

Quick Questions About This Study

Researchers exposed rat brain neurons to weak static magnetic fields (50 gauss) for seven days and found these fields provided significant protection against cell death. The magnetic field exposure reduced neuron death by 57% when cells were exposed to a toxic chemical, and decreased multiple markers of cellular damage by 40-80%. This suggests static magnetic fields might influence brain cell survival through changes in calcium channels.