Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels.
Nazıroğlu M, Özkan FF, Hapil SR, Ghazizadeh V, Çiğ B · 2015
View Original AbstractMobile phone radiation didn't worsen brain damage in epileptic rats, but this doesn't address effects on healthy brain tissue.
Plain English Summary
Turkish researchers exposed brain cells from epileptic rats to 900 MHz mobile phone radiation for one hour to see if it would worsen brain damage. They found that epilepsy itself caused significant cell death and oxidative stress in the hippocampus (the brain's memory center), but adding mobile phone radiation didn't make these effects any worse. This suggests that in already-damaged brain tissue, short-term mobile phone exposure may not add additional harm beyond what the underlying condition already causes.
Why This Matters
This study offers a nuanced finding that challenges simple assumptions about EMF effects on compromised neural tissue. While the researchers found no additional harm from 900 MHz exposure in epileptic brain cells, this doesn't mean EMF is harmless to healthy brain tissue. The reality is that diseased cells may respond differently to EMF exposure than healthy ones, and one hour of exposure may not capture longer-term effects that concern many researchers. What this means for you is that we still need more research on how EMF affects healthy brain tissue over extended periods. The study's focus on TRPV1 channels is particularly relevant because these heat-sensitive channels have been implicated in other EMF research, suggesting a potential biological mechanism worth investigating further.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 1 h
Study Details
We investigated the effects of mobile phone (900 MHz) EMR exposure on Ca(2+) influx, apoptosis, oxidative stress, and TRPV1 channel activations in the hippocampus of pentylenetetrazol (PTZ)-induced epileptic rats.
Freshly isolated hippocampal neurons of twenty-one rats were used in study within three groups namel...
The apoptosis, mitochondrial membrane depolarization, intracellular reactive oxygen species (ROS), a...
In conclusion, apoptosis, mitochondrial, ROS, and Ca(2+) influx via TRPV1 channel were increased in the hippocampal neurons by epilepsy induction although the mobile phone did not change the values. The results indicated that TRPV1 channels in hippocampus may possibly be a novel target for effective target of epilepsy.
Show BibTeX
@article{m_2015_epilepsy_but_not_mobile_2468,
author = {Nazıroğlu M and Özkan FF and Hapil SR and Ghazizadeh V and Çiğ B},
title = {Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels.},
year = {2015},
url = {https://pubmed.ncbi.nlm.nih.gov/25381485/},
}