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Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels.

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Nazıroğlu M, Özkan FF, Hapil SR, Ghazizadeh V, Çiğ B · 2015

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Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 1 h

Study Details

We investigated the effects of mobile phone (900 MHz) EMR exposure on Ca(2+) influx, apoptosis, oxidative stress, and TRPV1 channel activations in the hippocampus of pentylenetetrazol (PTZ)-induced epileptic rats.

Freshly isolated hippocampal neurons of twenty-one rats were used in study within three groups namel...

The apoptosis, mitochondrial membrane depolarization, intracellular reactive oxygen species (ROS), a...

In conclusion, apoptosis, mitochondrial, ROS, and Ca(2+) influx via TRPV1 channel were increased in the hippocampal neurons by epilepsy induction although the mobile phone did not change the values. The results indicated that TRPV1 channels in hippocampus may possibly be a novel target for effective target of epilepsy.

Cite This Study
Nazıroğlu M, Özkan FF, Hapil SR, Ghazizadeh V, Çiğ B (2015). Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels. J Membr Biol. 248(1):83-91, 2015.
Show BibTeX
@article{m_2015_epilepsy_but_not_mobile_2468,
  author = {Nazıroğlu M and Özkan FF and Hapil SR and Ghazizadeh V and Çiğ B},
  title = {Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels.},
  year = {2015},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/25381485/},
}
PubMed: 25381485

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