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Epilepsy But Not Mobile Phone Frequency (900 MHz) Induces Apoptosis and Calcium Entry in Hippocampus of Epileptic Rat: Involvement of TRPV1 Channels.

No Effects Found

Nazıroğlu M, Ozkan FF, Hapil SR, Ghazizadeh V, Ciğ B · 2015

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Mobile phone radiation didn't worsen brain damage in epileptic rats, but this doesn't prove safety for healthy brains.

Plain English Summary

Summary written for general audiences

Researchers exposed brain cells from epileptic rats to 900 MHz mobile phone radiation for one hour to see if it worsened seizure-related brain damage. The epilepsy itself caused significant cell death, oxidative stress, and calcium influx in the hippocampus (a brain region crucial for memory), but the mobile phone radiation didn't add any additional harmful effects. This suggests that in already-damaged brain tissue, 900 MHz EMF exposure may not worsen the cellular damage beyond what the disease itself causes.

Study Details

We investigated the effects of mobile phone (900 MHz) EMR exposure on Ca2+ influx, apoptosis, oxidative stress, and TRPV1 channel activations in the hippocampus of pentylenetetrazol (PTZ)-induced epileptic rats.

Freshly isolated hippocampal neuronThe neurons in PTZ + EMR group were exposed to the 900 MHz EMR fo...

The neurons in PTZ + EMR group were exposed to the 900 MHz EMR for 1 h. The apoptosis, mitochondrial...

The results indicated that TRPV1 channels in hippocampus may possibly be a novel target for effective target of epilepsy.

Cite This Study
Nazıroğlu M, Ozkan FF, Hapil SR, Ghazizadeh V, Ciğ B (2015). Epilepsy But Not Mobile Phone Frequency (900 MHz) Induces Apoptosis and Calcium Entry in Hippocampus of Epileptic Rat: Involvement of TRPV1 Channels. J Membr Biol 2015; 248 (1): 83-91.
Show BibTeX
@article{m_2015_epilepsy_but_not_mobile_2787,
  author = {Nazıroğlu M and Ozkan FF and Hapil SR and Ghazizadeh V and Ciğ B},
  title = {Epilepsy But Not Mobile Phone Frequency (900 MHz) Induces Apoptosis and Calcium Entry in Hippocampus of Epileptic Rat: Involvement of TRPV1 Channels.},
  year = {2015},
  doi = {10.1007/s00232-014-9744-y},
  url = {https://link.springer.com/article/10.1007/s00232-014-9744-y},
}

Quick Questions About This Study

Researchers exposed brain cells from epileptic rats to 900 MHz mobile phone radiation for one hour to see if it worsened seizure-related brain damage. The epilepsy itself caused significant cell death, oxidative stress, and calcium influx in the hippocampus (a brain region crucial for memory), but the mobile phone radiation didn't add any additional harmful effects. This suggests that in already-damaged brain tissue, 900 MHz EMF exposure may not worsen the cellular damage beyond what the disease itself causes.