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Impact of 2.45 GHz microwave radiation on the testicular inflammatory pathway biomarkers in young rats: The role of gallic acid.

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Saygin M, Asci H, Ozmen O, Cankara FN, Dincoglu D, Ilhan I. · 2015

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Daily WiFi-frequency radiation damaged rat testes through oxidative stress and inflammation, but antioxidant treatment provided significant protection.

Plain English Summary

Summary written for general audiences

Researchers exposed young male rats to 2.45 GHz microwave radiation (the same frequency used by WiFi and microwaves) for 3 hours daily over 30 days and found significant damage to their testes. The radiation increased oxidative stress, triggered inflammation, and reduced sperm production in the animals' reproductive organs. However, when rats received gallic acid (a natural antioxidant) alongside the radiation exposure, it protected against much of this testicular damage.

Why This Matters

This study adds to mounting evidence that 2.45 GHz radiation can damage male reproductive health through oxidative stress and inflammation. The frequency tested is identical to what your WiFi router, microwave oven, and many Bluetooth devices emit daily. What makes this research particularly significant is that it demonstrates a clear biological mechanism for how EMF exposure harms reproductive tissue, while also showing that antioxidant protection can help. The science demonstrates that prolonged exposure to common wireless frequencies can disrupt the delicate cellular environment needed for healthy sperm production. While this was an animal study, the biological pathways involved are fundamentally similar in humans, making these findings highly relevant to anyone concerned about fertility and reproductive health in our wireless world.

Exposure Information

Specific exposure levels were not quantified in this study. The study examined exposure from: 2.45 GHz Duration: 3 h day-1 for 30 days

Study Details

The aim of this study was to investigate electromagnetic radiation (EMR) transmitted by wireless devices (2.45 GHz), which may cause physiopathological or ultrastructural changes, in the testes of rats.

Six-week-old male Sprague Dawley rats were used in this study. Forty eight rats were equally divided...

Malondialdehyde (MDA) and total oxidant status (TOS) levels increased (p = 0.001 for both) in EMR on...

All these findings and the regenerative reaction, characterized by mitotic activity, increased in seminiferous tubules cells of the testes in EMR+GA group (p < 0.001). Long term EMR exposure resulted in testicular physiopathology via oxidative damage and inflammation. GA may have ameliorative effects on the prepubertal rat testes physiopathology.

Cite This Study
Saygin M, Asci H, Ozmen O, Cankara FN, Dincoglu D, Ilhan I. (2015). Impact of 2.45 GHz microwave radiation on the testicular inflammatory pathway biomarkers in young rats: The role of gallic acid. Environ Toxicol. 2015 Aug 13. doi: 10.1002/tox.22179.
Show BibTeX
@article{m_2015_impact_of_245_ghz_1703,
  author = {Saygin M and Asci H and Ozmen O and Cankara FN and Dincoglu D and Ilhan I.},
  title = {Impact of 2.45 GHz microwave radiation on the testicular inflammatory pathway biomarkers in young rats: The role of gallic acid.},
  year = {2015},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/26268881/},
}

Quick Questions About This Study

Researchers exposed young male rats to 2.45 GHz microwave radiation (the same frequency used by WiFi and microwaves) for 3 hours daily over 30 days and found significant damage to their testes. The radiation increased oxidative stress, triggered inflammation, and reduced sperm production in the animals' reproductive organs. However, when rats received gallic acid (a natural antioxidant) alongside the radiation exposure, it protected against much of this testicular damage.