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Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices.

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Oksay T, Naziroğlu M, Doğan S, Güzel A, Gümral N, Koşar PA. · 2012

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Wireless 2.45 GHz EMR caused oxidative damage in rat testis by increasing lipid peroxidation and decreasing vitamins A and E, and melatonin supplementation prevented this damage.

Plain English Summary

Summary written for general audiences

Thirty-two rats were equally divided into four groups: cage control, sham control, 2.45-GHz EMR exposure, and 2.45-GHz EMR plus melatonin. Rats in the EMR groups were exposed to 2.45-GHz EMR for 60 minutes per day for 30 days. EMR exposure increased lipid peroxidation and decreased vitamins A and E in the testis. Melatonin treatment prevented the rise in lipid peroxidation and the drop in vitamin E.

Why This Matters

The study aimed to test whether melatonin could protect against oxidative testis injury from 2.45-GHz EMR. The researchers also reported higher reduced glutathione and glutathione peroxidase levels in a group (Group D) compared to the exposure group.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 2.45 GHz Duration: 60 min day−1 for 30 days

Study Details

The present study was designed to determine the possible protective effects of melatonin on oxidative stress–dependent testis injury induced by 2.45-GHz electromagnetic radiation (EMR).

Thirty-two rats were equally divided into four different groups, namely cage control (A1), sham cont...

Lipid peroxidation levels were higher in Group B than in Group A1 and A2. Melatonin treatment preven...

In conclusion, wireless (2.45 GHz) EMR caused oxidative damage in testis by increasing the levels of lipid peroxidation and decreasing in vitamin A and E levels. Melatonin supplementation prevented oxidative damage induced by EMR and also supported the antioxidant redox system in the testis.

Cite This Study
Oksay T, Naziroğlu M, Doğan S, Güzel A, Gümral N, Koşar PA. (2012). Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices. Andrologia. 2012 Nov 12. doi: 10.1111/and.12044.
Show BibTeX
@article{t_2012_protective_effects_of_melatonin_1682,
  author = {Oksay T and Naziroğlu M and Doğan S and Güzel A and Gümral N and Koşar PA.},
  title = {Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices.},
  year = {2012},
  doi = {10.1111/and.12044},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1111/and.12044},
}
DOI: 10.1111/and.12044

Cited By (68 papers)

View all 68 citing papers on Semantic Scholar

Quick Questions About This Study

Rats were exposed to 2.45-GHz EMR for 60 minutes per day for 30 days.
EMR increased lipid peroxidation and decreased vitamins A and E.
Melatonin prevented the increase in lipid peroxidation and the decrease in vitamin E.
Reduced glutathione and glutathione peroxidase levels in Group D were higher than in the exposure group.