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Oxidative stress response in SH-SY5Y cells exposed to short-term 1800 MHz radiofrequency radiation

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Marjanovic Cermak AM, Pavicic I, Trosic I · 2018

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Short-term exposure to 1800 MHz radiofrequency radiation at non-thermal levels enhanced oxidative stress markers in neuroblastoma cells despite maintained cell viability.

Plain English Summary

Summary written for general audiences

This study exposed human neuroblastoma cells (SH-SY5Y) to 1800 MHz radiofrequency radiation at non-thermal levels for short durations (10-60 minutes) and measured oxidative stress markers. The researchers found increased reactive oxygen species (ROS) levels at all exposure times, significant lipid and protein damage after 60 minutes of exposure, and elevated antioxidant activity after 10 minutes, while cell viability remained normal.

Why This Matters

This in vitro study addresses the proposed mechanism of non-thermal RF effects through oxidative stress pathways. The findings are limited to cultured cells and do not directly translate to whole-organism or in vivo effects.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
Marjanovic Cermak AM, Pavicic I, Trosic I (2018). Oxidative stress response in SH-SY5Y cells exposed to short-term 1800 MHz radiofrequency radiation.
Show BibTeX
@article{marjanovic_cermak_am_pavicic_i_trosic_i_ce2504,
  author = {Marjanovic Cermak AM and Pavicic I and Trosic I},
  title = {Oxidative stress response in SH-SY5Y cells exposed to short-term 1800 MHz radiofrequency radiation},
  year = {2018},
  doi = {10.1016/j.jtemb.2017.12.003},
  
}
DOI: 10.1016/j.jtemb.2017.12.003PubMed: 29148897

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