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Oxidative Stress

Effects of 837 and 1950 MHz radiofrequency radiation exposure alone or combined on oxidative stress in MCF10A cells.

No Effects Found

Hong MN, Kim BC, Ko YG, Lee YS, Hong SC, Kim T, Pack JK, Choi HD, Kim N, Lee JS. · 2012

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Cell phone frequencies at four times legal exposure limits showed no oxidative stress in breast cells during 2-hour laboratory exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed human breast tissue cells to cell phone frequencies (837 MHz and 1950 MHz) at high power levels for 2 hours to test whether radiofrequency radiation causes oxidative stress, a type of cellular damage linked to disease. The study found no signs of oxidative stress in the cells, even when exposed to both frequencies simultaneously. This suggests that under these specific laboratory conditions, RF radiation did not trigger the cellular damage processes that scientists look for as early warning signs of health effects.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 837 MHz - 1.95 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 837 MHz - 1.95 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 837 MHz and 1950 MHz Duration: 2h

Study Details

The aim of this study was to determine whether the exposure to either single or multiple radio-frequency (RF) radiation frequencies could induce oxidative stress in cell cultures.

Exposures of human MCF10A mammary epithelial cells to either a single frequency (837 MHz alone or 19...

Intracellular levels of reactive oxygen species (ROS), the antioxidant enzyme activity of superoxide...

These results indicate that single or multiple RF radiation exposure did not elicit oxidative stress in MCF10A cells under our exposure conditions

Cite This Study
Hong MN, Kim BC, Ko YG, Lee YS, Hong SC, Kim T, Pack JK, Choi HD, Kim N, Lee JS. (2012). Effects of 837 and 1950 MHz radiofrequency radiation exposure alone or combined on oxidative stress in MCF10A cells. Bioelectromagnetics. 33(7):604-611, 2012.
Show BibTeX
@article{mn_2012_effects_of_837_and_2876,
  author = {Hong MN and Kim BC and Ko YG and Lee YS and Hong SC and Kim T and Pack JK and Choi HD and Kim N and Lee JS.},
  title = {Effects of 837 and 1950 MHz radiofrequency radiation exposure alone or combined on oxidative stress in MCF10A cells.},
  year = {2012},
  doi = {10.1002/bem.21731},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.21731},
}
DOI: 10.1002/bem.21731

Cited By (23 papers)

Quick Questions About This Study

A 2012 study found no oxidative stress in human breast tissue cells exposed to 837 MHz and 1950 MHz radiofrequency radiation for 2 hours at high power levels. The cells showed no changes in reactive oxygen species or antioxidant enzyme activity, suggesting these specific cell phone frequencies don't trigger cellular damage under laboratory conditions.
Research testing both 837 MHz and 1950 MHz frequencies simultaneously found no cellular damage in human breast tissue cells. The study measured multiple oxidative stress markers and found no significant changes, even when cells were exposed to both frequencies together for 2 hours at high power levels.
A laboratory study exposed human breast tissue cells to 837 MHz and 1950 MHz radiation for 2 hours without detecting oxidative stress or cellular damage. The cells maintained normal antioxidant enzyme activity and showed no signs of the reactive oxygen species that typically indicate cellular harm.
Human breast tissue cells exposed to 837 MHz and 1950 MHz radiation showed no changes in superoxide dismutase enzyme activity or glutathione ratios. A 2012 study found these important cellular antioxidant systems remained stable even after 2-hour exposures to high-power radiofrequency radiation.
MCF10A human breast cells showed no sensitivity to high-power 837 MHz and 1950 MHz radiofrequency radiation in laboratory testing. Despite 2-hour exposures that would reveal cellular damage, researchers found no oxidative stress markers or changes in the cells' antioxidant defense systems.