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Assessment of the neurotoxic potential of exposure to 50 Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells

No Effects Found

de Groot MW, Kock MD, Westerink RH. · 2014

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Nerve cells showed no damage from 50 Hz magnetic fields at 1,000 microtesla, which is 1,000 times stronger than power line exposure.

Plain English Summary

Summary written for general audiences

Dutch researchers exposed nerve cells (PC12 cells) to 50 Hz magnetic fields at levels up to 1,000 microtesla for periods ranging from 30 minutes to 48 hours. They found no effects on calcium levels, oxidative stress, or cell membrane integrity, even in cells that had been chemically stressed to make them more vulnerable. The exposure levels were 10,000 times higher than typical background magnetic field exposure.

Study Details

We investigated effects of acute (30 min) and sub-chronic (48 h) exposure to 50 Hz ELF-EMF on naïve and chemically stressed pheochromocytoma (PC12) cells.

The latter have higher levels of iron and/or reactive oxygen species (ROS) and display increased vu...

Our data demonstrate that acute exposure of naïve PC12 cells to 50 Hz ELF-EMF up to 1000 μT fails to...

Though our data require confirmation, e.g. in developing neuronal cells in vitro or (developing) animals, it appears that the neurotoxic risk of ELF-EMF exposure is limited.

Cite This Study
de Groot MW, Kock MD, Westerink RH. (2014). Assessment of the neurotoxic potential of exposure to 50 Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells Neurotoxicology. 2014 :doi: 10.1016/j.neuro.2014.07.009.
Show BibTeX
@article{mw_2014_assessment_of_the_neurotoxic_2825,
  author = {de Groot MW and Kock MD and Westerink RH. },
  title = {Assessment of the neurotoxic potential of exposure to 50 Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells},
  year = {2014},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0161813X14001387},
}

Quick Questions About This Study

Dutch researchers exposed nerve cells (PC12 cells) to 50 Hz magnetic fields at levels up to 1,000 microtesla for periods ranging from 30 minutes to 48 hours. They found no effects on calcium levels, oxidative stress, or cell membrane integrity, even in cells that had been chemically stressed to make them more vulnerable. The exposure levels were 10,000 times higher than typical background magnetic field exposure.