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Electromagnetic field effect or simply stress? Effects of UMTS exposure on hippocampal longterm plasticity in the context of procedure related hormone release.

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Prochnow N, Gebing T, Ladage K, Krause-Finkeldey D, El Ouardi A, Bitz A, Streckert J, Hansen V, Dermietzel R. · 2011

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High-level 3G exposure (10 W/kg) impaired memory formation in rat brains, while moderate levels (2 W/kg) showed no effects.

Plain English Summary

Summary written for general audiences

German researchers exposed rats to 3G cell phone radiation at different power levels for two hours. Low exposure (2 W/kg) caused no memory problems, but high exposure (10 W/kg) significantly impaired the brain's ability to form memories, suggesting a threshold for wireless radiation effects.

Why This Matters

This study provides important evidence for a dose-response relationship in EMF exposure - meaning higher exposure levels produce more pronounced biological effects. The 10 W/kg exposure level that caused memory impairment is well above typical cell phone use (which produces SAR levels around 0.5-1.6 W/kg), but the finding of measurable brain effects is significant. What makes this research particularly valuable is its careful methodology, including blinded exposure conditions and accounting for stress-related confounding factors. The researchers distinguished between general stress responses and EMF-specific effects, strengthening their conclusions about wireless radiation's direct impact on hippocampal function - the brain region critical for learning and memory formation.

Exposure Details

SAR
0, 2, and 10 W/kg
Exposure Duration
120 min

Exposure Context

This study used 0, 2, and 10 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0, 2, and 10 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 1x higher than this exposure level

Study Details

In the present study we applied radio-frequency (RF) signals of the Universal Mobile Telecommunications System (UMTS) to full brain exposed male Wistar rats in order to elaborate putative influences on stress hormone release (corticosteron; CORT and adrenocorticotropic hormone; ACTH) and on hippocampal derived synaptic long-term plasticity (LTP) and depression (LTD) as electrophysiological hallmarks for memory storage and memory consolidation.

Exposure was computer controlled providing blind conditions. Nominal brain-averaged specific absorpt...

Comparison of cage exposed animals revealed, regardless of EMF exposure, significantly increased COR...

Our findings suggest that UMTS exposure with SAR in the range of 2 W/kg is not harmful to critical markers for memory storage and memory consolidation, however, an influence of UMTS at high energy absorption rates (10 W/kg) cannot be excluded.

Cite This Study
Prochnow N, Gebing T, Ladage K, Krause-Finkeldey D, El Ouardi A, Bitz A, Streckert J, Hansen V, Dermietzel R. (2011). Electromagnetic field effect or simply stress? Effects of UMTS exposure on hippocampal longterm plasticity in the context of procedure related hormone release. PLoS One. 6(5):e19437, 2011.
Show BibTeX
@article{n_2011_electromagnetic_field_effect_or_1276,
  author = {Prochnow N and Gebing T and Ladage K and Krause-Finkeldey D and El Ouardi A and Bitz A and Streckert J and Hansen V and Dermietzel R.},
  title = {Electromagnetic field effect or simply stress? Effects of UMTS exposure on hippocampal longterm plasticity in the context of procedure related hormone release.},
  year = {2011},
  
  url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019437},
}

Quick Questions About This Study

German researchers exposed rats to 3G cell phone radiation at different power levels for two hours. Low exposure (2 W/kg) caused no memory problems, but high exposure (10 W/kg) significantly impaired the brain's ability to form memories, suggesting a threshold for wireless radiation effects.