6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

Cerebral radiofrequency exposures during adolescence: Impact on astrocytes and brain functions in healthy and pathologic rat models.

No Effects Found

Petitdant N, Lecomte A, Robidel F, Gamez C, Blazy K, Villégier AS · 2016

View Original Abstract
Share:

Rats exposed to RF EMF during adolescence showed no neurobiological impairment, even after neurodevelopmental inflammation.

Plain English Summary

Summary written for general audiences

Researchers used rats to assess whether astrocyte reactivity, perception, and emotionality were affected by RF EMF exposures during adolescence. They also investigated if adolescent brains were more sensitive to RF EMF exposures after neurodevelopmental inflammation. Results did not show any neurobiological impairment in healthy and vulnerable RF EMF-exposed rats compared to sham-exposed controls. Data did not support the hypothesis of a specific cerebral sensitivity to RF EMF of adolescents, even after neurodevelopmental inflammation.

Why This Matters

Researchers performed 80 μg/kg intra-peritoneal injections of lipopolysaccharides during gestation or 1.25 μg/h intra-cerebro-ventricular infusions during adolescence to model neurodevelopmental inflammation. From postnatal day 32 to 62, rats were subjected to 45-minute RF EMF exposures to the brain at specific absorption rates of 0, 1.5, or 6 W/kg, five days per week.

Exposure Details

SAR
0, 1.5, or 6 W/kg
Exposure Duration
45 min 5 days/week

Exposure Context

This study used 0, 1.5, or 6 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0, 1.5, or 6 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 1 times higher than this level

Study Details

Here, we used rats to assess whether astrocyte reactivity, perception, and emotionality were affected by RF EMF exposures during adolescence. We also investigated if adolescent brains were more sensitive to RF EMF exposures after neurodevelopmental inflammation.

To do so, we either performed 80 μg/kg intra-peritoneal injections of lipopolysaccharides during ges...

Our results did not show any neurobiological impairment in healthy and vulnerable RF EMF-exposed rat...

These data did not support the hypothesis of a specific cerebral sensitivity to RF EMF of adolescents, even after a neurodevelopmental inflammation.

Cite This Study
Petitdant N, Lecomte A, Robidel F, Gamez C, Blazy K, Villégier AS (2016). Cerebral radiofrequency exposures during adolescence: Impact on astrocytes and brain functions in healthy and pathologic rat models. Bioelectromagnetics. 37(5):338-350, 2016.
Show BibTeX
@article{n_2016_cerebral_radiofrequency_exposures_during_3302,
  author = {Petitdant N and Lecomte A and Robidel F and Gamez C and Blazy K and Villégier AS},
  title = {Cerebral radiofrequency exposures during adolescence: Impact on astrocytes and brain functions in healthy and pathologic rat models.},
  year = {2016},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/27272062/},
}
PubMed: 27272062

Cited By (14 papers)

Quick Questions About This Study

The study investigated whether astrocyte reactivity, perception, and emotionality were affected by RF EMF exposures during adolescence, and if adolescent brains were more sensitive after neurodevelopmental inflammation.
The results did not show any neurobiological impairment in healthy and vulnerable RF EMF-exposed rats compared to sham-exposed controls, and the data did not support the hypothesis of a specific cerebral sensitivity to RF EMF of adolescents, even after neurodevelopmental inflammation.
From postnatal day 32 to 62, rats were subjected to 45-minute RF EMF exposures to the brain at specific absorption rates of 0, 1.5, or 6 W/kg, five days per week.
Researchers performed 80 μg/kg intra-peritoneal injections of lipopolysaccharides during gestation or 1.25 μg/h intra-cerebro-ventricular infusions during adolescence.
Rats were tested for perception of novelty, anxiety-like behaviors, and emotional memory.