8,700 Studies Reviewed. 87.0% Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.

No Effects Found

Park J, Kwon JH, Kim N, Song K · 2017

View Original Abstract
Share:

Short-term cell phone radiation showed no immediate effects on Alzheimer's-related brain proteins, but long-term impacts remain unknown.

Plain English Summary

Summary written for general audiences

Researchers exposed brain cells to cell phone radiation (1950 MHz) for 2 hours daily over 3 days to see if it affected amyloid-beta processing, which is linked to Alzheimer's disease. They found no significant changes in the proteins that create these brain plaques. However, the researchers noted that longer-term exposure might produce different results than their short 3-day study.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.95 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.95 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 1950 MHz Duration: 2 h per day for 3 days

Study Details

In this study, we examined whether exposure to 1950 MHz RF-EMF affects Aβ processing in neural cells.

We exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to RF-EMF (SA...

When exposed to RF-EMF, mRNA levels of APP, BACE1, ADAM10 and PSEN1 were decreased in HT22, but the ...

These observations suggest that RF-EMF exposure may not have a significant physiological effect on Aβ processing of neural cells in the short term. However, considering that we only exposed HT22 and SH-SY5Y cells to RF-EMF for 2 h per day for 3 days, we cannot exclude the possibility that 1950 MHz RF-EMF induces physiological change in Aβ processing with long-term and continuous exposure.

Cite This Study
Park J, Kwon JH, Kim N, Song K (2017). Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells. J Radiat Res. 2017 Oct 6:1-9. doi: 10.1093/jrr/rrx045.
Show BibTeX
@article{j_2017_effects_of_1950_mhz_3297,
  author = {Park J and Kwon JH and Kim N and Song K},
  title = {Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.},
  year = {2017},
  
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778507/},
}

Quick Questions About This Study

A 2017 study found that 1950 MHz radiation exposure for 2 hours daily over 3 days did not significantly change amyloid-beta proteins linked to Alzheimer's disease in brain cells. However, researchers noted that longer-term exposure might produce different results than this short study.
Research shows that exposing neuroblastoma and hippocampal cells to 1950 MHz radiation for 2 hours daily over 3 days did not significantly alter proteins involved in brain plaque formation. The study suggests short-term RF exposure may not affect amyloid processing in neural cells.
A laboratory study found no significant physiological effects on hippocampal neurons after 3 days of 1950 MHz exposure. While short-term exposure appeared safe, researchers cautioned that continuous long-term exposure might produce different results in amyloid-beta processing.
When neuroblastoma cells were exposed to 1950 MHz radiation for 2 hours daily over 3 days, researchers found no significant changes in amyloid-beta peptide secretion or key protein expressions. The study suggests minimal short-term impact on these brain-derived cells.
Research found that 1950 MHz radiation decreased some mRNA levels in mouse hippocampal cells but didn't change APP gene expression in human neuroblastoma cells. Overall protein levels remained unchanged, suggesting limited impact from short-term exposure on brain cell genetics.