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Effects of Long Term Exposure of 900-1800 MHz Radiation Emitted from 2G Mobile Phone on Mice Hippocampus- A Histomorphometric Study.

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Mugunthan N, Shanmugasamy K, Anbalagan J, Rajanarayanan S, Meenachi S. · 2016

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Six months of mobile phone radiation exposure caused measurable brain cell damage in the hippocampus, the brain's memory center.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to 2G mobile phone radiation (900-1800 MHz) for 48 minutes daily over six months and examined their brain tissue under a microscope. They found that the radiation caused significant changes in the hippocampus (the brain's memory center), including reduced numbers of neurons in key areas and smaller cell nuclei throughout the region. These cellular changes suggest that chronic mobile phone radiation exposure may damage the brain structures responsible for learning and memory.

Why This Matters

This study adds to mounting evidence that radiofrequency radiation affects brain structure at the cellular level. The hippocampus is critical for memory formation and learning, making these findings particularly concerning for heavy mobile phone users. The exposure duration of 48 minutes daily mirrors realistic usage patterns for many people, especially children who often spend hours on phones and tablets. What makes this research significant is its focus on long-term exposure rather than acute effects. The science demonstrates that chronic RF exposure can alter neuron density and cellular structure in ways that could potentially impact cognitive function. While this was an animal study, the biological mechanisms involved are similar across mammalian species, suggesting these effects may translate to humans.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 to 1800 MHz

Study Details

To investigate the long term exposure of 900 to 1800 MHz radiations emitted from 2G mobile phone in mice hippocampus at histomorphometric level.

With due approval from institutional animal ethics committee, 36 mice were exposed to 2G mobile phon...

The mean density of neurons in the hippocampus regions CA1, CA2 and DGDB from first to sixth month w...

The long term exposure to 900-1800 MHz frequency radiations emitted from 2G mobile phone could cause significantly reduced neuron density and decreased nuclear diameter in the hippocampus neurons of mice.

Cite This Study
Mugunthan N, Shanmugasamy K, Anbalagan J, Rajanarayanan S, Meenachi S. (2016). Effects of Long Term Exposure of 900-1800 MHz Radiation Emitted from 2G Mobile Phone on Mice Hippocampus- A Histomorphometric Study. J Clin Diagn Res. 2016 Aug;10(8):AF01-6.
Show BibTeX
@article{n_2016_effects_of_long_term_2450,
  author = {Mugunthan N and Shanmugasamy K and Anbalagan J and Rajanarayanan S and Meenachi S. },
  title = {Effects of Long Term Exposure of 900-1800 MHz Radiation Emitted from 2G Mobile Phone on Mice Hippocampus- A Histomorphometric Study.},
  year = {2016},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/27656427/},
}
PubMed: 27656427

Cited By (18 papers)

Quick Questions About This Study

Yes, a 2016 study found that 48 minutes of daily 2G radiation (900-1800 MHz) for six months significantly reduced neuron density in key hippocampus regions and decreased nuclear diameter in brain cells responsible for memory and learning in mice.
Research shows 900-1800 MHz radiation from 2G phones causes significant cellular changes in the hippocampus, the brain's memory center. Six months of exposure reduced neuron numbers in critical areas and shrank cell nuclei throughout this region.
Chronic 2G phone radiation exposure significantly reduces neuron density in the CA1 and CA2 hippocampus regions. A six-month study found these memory-critical brain areas showed measurably fewer neurons after daily 900-1800 MHz radiation exposure.
Six months of 2G radiation exposure decreases the nuclear diameter of hippocampus neurons across all brain regions studied. This cellular shrinkage occurred in CA1, CA2, CA3, and dentate gyrus areas, suggesting widespread impact on brain cell structure.
Histomorphometric analysis reveals 2G phone radiation causes measurable brain damage in mice. Microscopic examination showed reduced neuron density in memory regions and smaller cell nuclei after six months of daily 900-1800 MHz exposure for 48 minutes.