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Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice.

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Pandey N, Giri S, Das S, Upadhaya P. · 2016

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Cell phone frequency radiation significantly damaged sperm-producing cells and reduced sperm counts in mice after 35 days of exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed male mice to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 4-8 hours daily for 35 days to study effects on sperm production. The radiation caused DNA damage in sperm-producing cells and disrupted the normal development process, resulting in significantly reduced sperm counts. While some recovery occurred after radiation exposure ended, the study demonstrates that RF radiation can impair male fertility through cellular damage.

Why This Matters

This study adds to mounting evidence that radiofrequency radiation affects male reproductive health through multiple biological pathways. The 900 MHz frequency used mirrors GSM cell phone emissions, making these findings directly relevant to daily phone use. What's particularly concerning is that the researchers found a 2.5-fold increase in damaged germ cells and a dramatic reduction in sperm production, with some cellular processes showing three to four-fold decreases in normal function. While the partial recovery after exposure ended offers some reassurance, the reality is that most men today face continuous RF exposure from phones, WiFi, and other wireless devices. The science demonstrates that RF radiation can disrupt the delicate cellular processes required for healthy sperm production, potentially contributing to declining male fertility rates observed globally.

Exposure Information

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 4 h and 8 h duration per day for 35 days

Study Details

This study evaluates alterations in male germ cell transformation kinetics following RFR exposure and after recovery.

Swiss albino mice were exposed to RFR (900 MHz) for 4 h and 8 h duration per day for 35 days. One gr...

Statistically significant increases in the damage index in germ cells and sperm head defects were no...

To conclude, RFR exposure-induced oxidative stress causes DNA damage in germ cells, which alters cell cycle progression leading to low sperm count in mice.

Cite This Study
Pandey N, Giri S, Das S, Upadhaya P. (2016). Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice. Toxicol Ind Health. 2016 Oct 13. pii: 0748233716671206.
Show BibTeX
@article{n_2016_radiofrequency_radiation_900_mhzinduced_1797,
  author = {Pandey N and Giri S and Das S and Upadhaya P.},
  title = {Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice.},
  year = {2016},
  doi = {10.1177/0748233716671206},
  url = {https://journals.sagepub.com/doi/abs/10.1177/0748233716671206},
}

Quick Questions About This Study

Researchers exposed male mice to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 4-8 hours daily for 35 days to study effects on sperm production. The radiation caused DNA damage in sperm-producing cells and disrupted the normal development process, resulting in significantly reduced sperm counts. While some recovery occurred after radiation exposure ended, the study demonstrates that RF radiation can impair male fertility through cellular damage.