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Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation

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Cichoń N, Czarny P, Bijak M, Miller E, Śliwiński T, Szemraj J, Saluk-Bijak J · 2017

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ELF-EMF significantly increased 3-nitrotyrosine and nitrate/nitrite levels and improved functional and mental status in poststroke patients.

Plain English Summary

Summary written for general audiences

Patients were divided into two groups, both undergoing the same 4-week rehabilitation program, with one group also receiving daily ELF-EMF exposure. The ELF-EMF group was exposed to a field of 40 Hz and 7 mT for 15 minutes per day. ELF-EMF significantly increased 3-nitrotyrosine and nitrate/nitrite levels, while NOS2 expression was insignificantly decreased in both groups. The researchers concluded that ELF-EMF therapy is capable of promoting recovery in poststroke patients.

Why This Matters

The study aimed to investigate the effect of ELF-EMF on generation and metabolism of nitric oxide as a neurotransmitter in poststroke rehabilitation. Functional status was evaluated before and after treatments using the Activity Daily Living, Geriatric Depression Scale, and Mini-Mental State Examination. Levels of 3-nitrotyrosine, nitrate/nitrite, and TNFα in plasma were measured, and NOS2 expression was determined in whole blood samples.

Exposure Details

Magnetic Field
7 mT
Source/Device
40 Hz
Exposure Duration
15 min/day for 4 weeks

Exposure Context

This study used 7 mT for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 7 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)This level is 35 times the FCC limit
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 40 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 40 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Study Details

The aim of our study was to investigate the effect of the extremely low-frequency electromagnetic field (ELF-EMF) on generation and metabolism of NO, as a neurotransmitter, in the rehabilitation of poststroke patients.

Forty-eight patients were divided into two groups: ELF-EMF and non-ELF-EMF. Both groups underwent t...

We observed that application of ELF-EMF significantly increased 3-nitrotyrosine and nitrate/nitrite ...

We conclude that ELF-EMF therapy is capable of promoting recovery in poststroke patients.

Cite This Study
Cichoń N, Czarny P, Bijak M, Miller E, Śliwiński T, Szemraj J, Saluk-Bijak J (2017). Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation Oxid Med Cell Longev. 2017:2181942, 2017b.
Show BibTeX
@article{n_2017_benign_effect_of_extremely_334,
  author = {Cichoń N and Czarny P and Bijak M and Miller E and Śliwiński T and Szemraj J and Saluk-Bijak J},
  title = {Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation},
  year = {2017},
  
  url = {https://www.hindawi.com/journals/omcl/2017/2181942/},
}

Quick Questions About This Study

The study used an extremely low-frequency electromagnetic field of 40 Hz and 7 mT.
Each ELF-EMF session lasted 15 minutes per day.
ELF-EMF significantly increased 3-nitrotyrosine and nitrate/nitrite levels, while NOS2 expression was insignificantly decreased in both groups.
ELF-EMF treatments improved functional and mental status.
The researchers concluded that ELF-EMF therapy is capable of promoting recovery in poststroke patients.