6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

Evaluation of bax, bcl-2, p21 and p53 genes expression variations on cerebellum of BALB/c mice before and after birth under mobile phone radiation exposure.

No Effects Found

Ghatei N, Nabavi AS, Toosi MHB, Azimian H, Homayoun M, Targhi RG, Haghir H. · 2017

View Original Abstract
Share:

Mobile phone radiation decreased bax expression and increased p21 expression in mouse cerebellum, while bcl-2 and p53 expression were unchanged.

Plain English Summary

Summary written for general audiences

Researchers exposed pregnant BALB/c mice to mobile phone jammer radiation at 900 and 1800 MHz on the 19th day of pregnancy. After birth, offspring were divided into four exposure groups and examined at 8-10 weeks of age. Cerebellar expression of bax, bcl-2, p21, and p53 was measured by real-time RT-PCR. Radiation did not change bcl-2 or p53 expression (P>0.05). Radiation decreased bax expression and increased p21 expression compared to controls (P<0.05).

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 and 1800 MHz

Study Details

We examined the effect of mobile phones radiation on genes expression variation on cerebellum of BALB/c mice before and after of the birth.

In this study, a mobile phone jammer, which is an instrument to prevent receiving signals between ce...

The data showed that mobile phone radio waves were ineffective on the expression level of bcl-2 and ...

From the obtained data it could be concluded that the mobile phone radiations did not induce apoptosis in cells of the cerebellum and the injured cells can be repaired by cell cycle arrest.

Cite This Study
Ghatei N, Nabavi AS, Toosi MHB, Azimian H, Homayoun M, Targhi RG, Haghir H. (2017). Evaluation of bax, bcl-2, p21 and p53 genes expression variations on cerebellum of BALB/c mice before and after birth under mobile phone radiation exposure. Iran J Basic Med Sci. 20(9):1037-1043, 2017.
Show BibTeX
@article{n_2017_evaluation_of_bax_bcl2_3038,
  author = {Ghatei N and Nabavi AS and Toosi MHB and Azimian H and Homayoun M and Targhi RG and Haghir H.},
  title = {Evaluation of bax, bcl-2, p21 and p53 genes expression variations on cerebellum of BALB/c mice before and after birth under mobile phone radiation exposure.},
  year = {2017},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/29085599/},
}
PubMed: 29085599

Cited By (26 papers)

Quick Questions About This Study

A mobile phone jammer operating at 900 and 1800 MHz was used for exposure.
Twelve pregnant mice were divided into two groups, with one group irradiated on the 19th day of pregnancy. After birth, offspring were assigned to four groups: control, irradiated after birth, irradiated during pregnancy and after birth, and irradiated during pregnancy only.
Radiation decreased bax expression and increased p21 expression compared to the control group (P<0.05).
Radiation had no significant effect on bcl-2 or p53 expression (P>0.05).
They concluded that mobile phone radiation did not induce apoptosis in cerebellar cells and that injured cells could be repaired by cell cycle arrest.