Long term exposure to cell phone frequencies (900 and 1800 MHz) induces apoptosis, mitochondrial oxidative stress and TRPV1 channel activation in the hippocampus and dorsal root ganglion of rats.
Ertilav K, Uslusoy F, Ataizi S, Nazıroğlu M. · 2018
View Original AbstractYear-long cell phone frequency exposure caused measurable brain damage in rats, with higher frequencies producing more severe cellular death and oxidative stress.
Plain English Summary
Researchers exposed rats to cell phone frequencies (900 and 1800 MHz) for one hour daily, five days a week for an entire year, then examined brain tissue for damage. They found significant cellular damage including cell death, oxidative stress, and disrupted calcium channels in the hippocampus (memory center) and nerve tissues. The higher frequency (1800 MHz) caused more severe damage than the lower frequency, suggesting a dose-response relationship.
Why This Matters
This year-long study provides compelling evidence that chronic exposure to cell phone frequencies can cause measurable brain damage in living tissue. The researchers used exposure levels and frequencies that mirror real-world cell phone use, making their findings directly relevant to human health concerns. What makes this study particularly significant is the dose-response relationship they documented - higher frequencies caused more severe damage, which strengthens the case for biological causation rather than coincidence. The cellular mechanisms they identified (calcium channel disruption, oxidative stress, and programmed cell death) help explain how EMF exposure could contribute to neurological problems over time. While we can't directly extrapolate animal studies to humans, the biological pathways involved are fundamentally similar across species, making this research an important piece of the growing evidence base linking EMF exposure to brain health risks.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900 and 1800 MHz Duration: 60 min/ 5 days of the week during the one year
Study Details
We investigated the contribution TRPV1 to mitochondrial oxidative stress and apoptosis in HIPPON and DRGN following long term exposure to 900 and 1800 MHz in a rat model
Twenty-four adult rats were equally divided into the following groups: (1) control, (2) 900 MHz, and...
The 900 and 1800 MHz EMR exposure induced increases in TRPV1 currents, intracellular free calcium in...
In conclusion, mitochondrial oxidative stress, programmed cell death and Ca2+ entry pathway through TRPV1 activation in the HIPPON and DRGN of rats were increased in the rat model following exposure to 900 and 1800 MHz cell frequencies. Our results suggest that exposure to 900 and 1800 MHz EMR may induce a dose-associated, TRPV1-mediated stress response.
Show BibTeX
@article{k_2018_long_term_exposure_to_1632,
author = {Ertilav K and Uslusoy F and Ataizi S and Nazıroğlu M.},
title = {Long term exposure to cell phone frequencies (900 and 1800 MHz) induces apoptosis, mitochondrial oxidative stress and TRPV1 channel activation in the hippocampus and dorsal root ganglion of rats.},
year = {2018},
doi = {10.1007/s11011-017-0180-4},
url = {https://link.springer.com/article/10.1007/s11011-017-0180-4},
}