Pyramidal Cell Loss in the Cornu Ammonis of 32-day-old Female Rats Following Exposure to a 900 Megahertz Electromagnetic Field During Prenatal Days 13–21.
Baş O, Sönmez OF, Aslan A, İkinci A, Hancı H, Yıldırım M, Kaya H, Akça M, Odacı E · 2013
View Original AbstractFemale rat pups whose mothers were exposed to a 900 MHz electromagnetic field during pregnancy had significantly fewer pyramidal cells in the cornu ammonis of the hippocampus.
Plain English Summary
Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.
Why This Matters
Five newborn female rats came from the exposed group and six from the control group, and no procedures were applied to either group after birth. Brain sections were stained with Cresyl fast violet, and the optical dissector technique was used to estimate the total number of pyramidal cells in the cornu ammonis. The researchers suggest that the pyramidal cell loss may be attributed to the 900 MHz EMF exposure during prenatal days 13 through 21. The findings suggest that long-term exposure to 900 MHz EMF in the prenatal period affects neuron development in the hippocampus, and that this may result in a decrease in cell numbers in the postnatal period.
Exposure Details
- Power Density
- 0.0265 mW/cm²
- Electric Field
- 10 V/m
- Source/Device
- 900 MHz EMF
- Exposure Duration
- 60 min/day
Exposure Context
This study used 0.0265 mW/cm² for radio frequency:
- 2.7Mx above the Building Biology guideline of 0.1 μW/m²
- 44.2Kx above the BioInitiative Report recommendation of 0.0006 μW/cm²
This study used 10 V/m for electric fields:
- 33.3x above the Building Biology guideline of 0.3 V/m
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In this study we investigated the effect of a 900 MHz EMF applied on days 13-21 of the prenatal period on the number of pyramidal cells in the cornu ammonis of rat pups in the postnatal period.
For that purpose, pregnant rats were divided into experimental and control groups. Experimental grou...
Our results showed that exposure to 900 MHz EMF during prenatal days 13-21 led to a significant decr...
These findings suggest that longterm exposure to 900 MHz EMF in the prenatal period affects neuron development in the hippocampus, and that this may result in a decrease in cell numbers in the postnatal period.
Show BibTeX
@article{o_2013_pyramidal_cell_loss_in_69,
author = {Baş O and Sönmez OF and Aslan A and İkinci A and Hancı H and Yıldırım M and Kaya H and Akça M and Odacı E},
title = {Pyramidal Cell Loss in the Cornu Ammonis of 32-day-old Female Rats Following Exposure to a 900 Megahertz Electromagnetic Field During Prenatal Days 13–21.},
year = {2013},
url = {https://pdfs.semanticscholar.org/1f01/72be29358109062842914284195037ad1df9.pdf},
}