Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats.
Mokarram P, Sheikhi M, Mortazavi SMJ, Saeb S, Shokrpour N · 2017
View Original AbstractCell phone radiation altered cancer-related gene activity in rat colon cells after just 4 hours of exposure.
Plain English Summary
Researchers exposed male rats to 900 MHz GSM cell phone radiation for 4 hours and found it altered DNA methylation patterns in colon cells, specifically affecting the estrogen receptor gene. DNA methylation is a process that controls gene activity and plays a role in cancer development. This suggests that cell phone radiation may cause epigenetic changes that could potentially increase colorectal cancer risk.
Why This Matters
This study reveals a concerning mechanism by which cell phone radiation may contribute to cancer development. The researchers found that just 4 hours of GSM radiation exposure altered methylation patterns of the estrogen receptor gene in colon tissue. What makes this particularly significant is that these epigenetic changes can persist and potentially lead to abnormal cell growth over time. The 900 MHz frequency tested is identical to what GSM phones use, making these findings directly relevant to everyday cell phone exposure. While this was an animal study with limitations, it adds to the growing body of evidence that radiofrequency radiation can cause biological changes at the cellular level that may increase cancer risk.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz GSM Mobile Phone
Study Details
This study aimed to investigate whether epigenetic pattern of ERα is susceptible to RF radiation and if RF radiation can induce radioadaptive response as epigenetic changes after receiving the challenge dose (γ-ray).
40 male Sprague-Dawley rats were divided into 4 equal groups (Group I: exposure to RF radiation of a...
Our finding showed that exposure to GSM cell phone RF radiation was capable of altering the pattern ...
It can be concluded that exposure to RF radiation emitted by GSM mobile phones can lead to epigenetic detrimental changes in ERα promoter methylation pattern.
Show BibTeX
@article{p_2017_effect_of_exposure_to_2429,
author = {Mokarram P and Sheikhi M and Mortazavi SMJ and Saeb S and Shokrpour N},
title = {Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats.},
year = {2017},
url = {https://pubmed.ncbi.nlm.nih.gov/28451581/},
}