Proteomics analysis of human endothelial cell line EA.hy926 after exposure to GSM 900 radiation.
Nylund R, Leszczynski D · 2004
View Original AbstractCell phone radiation altered 38 proteins in blood vessel cells, disrupting cellular structure in ways that could affect cardiovascular function.
Plain English Summary
Researchers exposed human blood vessel cells to cell phone radiation and found that 38 different proteins changed their expression levels. Two of the affected proteins were vimentin, which helps maintain cell structure and shape. This suggests that cell phone radiation can disrupt the cellular skeleton that gives cells their form and helps them function properly.
Why This Matters
This research provides important mechanistic insight into how cell phone radiation affects living cells at the molecular level. The fact that GSM 900 MHz radiation - the same frequency used by many cell phones - altered the expression of nearly 40 proteins demonstrates that these exposures are biologically active, not biologically inert as the wireless industry often claims. The researchers' focus on vimentin is particularly significant because this protein is essential for maintaining cellular structure and enabling critical functions like cell division and migration. When the cellular skeleton is disrupted, it can cascade into broader physiological problems. What makes this study especially relevant is that it examines endothelial cells, which line our blood vessels and play crucial roles in cardiovascular health. The science demonstrates that everyday exposures from mobile phones can trigger measurable biological changes at the cellular level, adding to the growing body of evidence that these technologies are not as safe as we've been led to believe.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: GSM 900 MHz
Study Details
The human endothelial cell line EA.hy926 was exposed to mobile phone radiation and the effect on protein expression was examined using two-dimensional electrophoresis (2-DE).
Up to 38 various proteins have statistically significantly altered their expression levels following...
This finding supports our earlier presented working hypothesis which indicated that the mobile phone radiation might affect the cytoskeleton and might have an effect on the physiological functions that are regulated by the cytoskeleton.
Show BibTeX
@article{r_2004_proteomics_analysis_of_human_2474,
author = {Nylund R and Leszczynski D},
title = {Proteomics analysis of human endothelial cell line EA.hy926 after exposure to GSM 900 radiation.},
year = {2004},
url = {https://pubmed.ncbi.nlm.nih.gov/15188403/},
}